0000000000186344

AUTHOR

Verónica G. Vegas

showing 11 related works from this author

Rational Design of Copper(II)-Uracil Nanoprocessed Coordination Polymers to Improve Their Cytotoxic Activity in Biological Media

2021

This work is focused on the rational structural design of two isostructural Cu(II) nano-coordination polymers (NCPs) with uracil-1-acetic acid (UAcOH) (CP1n) and 5-fluorouracil-1-acetic acid (CP2n). Suitable single crystals for ꭕ-ray diffraction studies of CP1 and CP2 were prepared under hydrothermal conditions, enabling their structural determination as 1D-CP ladder-like polymeric structures. The control of the synthetic parameters allows their processability into water colloids based on nanoplates (CP1n and CP2n). These NCPs are stable in water at physiological pHs for long periods. However, interestingly, CP1n is chemically altered in culture media. These transformations provoke the part…

Materials scienceCell SurvivalPolymersCytotoxicitychemistry.chemical_elementAntineoplastic Agentschemistry.chemical_compoundHydrolysisBiological mediaCoordination ComplexesCell Line TumorMoietyHumansGeneral Materials Science5-fluorouracilIsostructuralCytotoxicityUracilchemistry.chemical_classificationReactive oxygen speciesRational designUracilQuímicaCombinatorial chemistryCopperCoordination polymerschemistryNano-coordination polymersReactive Oxygen SpeciesCopper
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Copper(II)–Thymine Coordination Polymer Nanoribbons as Potential Oligonucleotide Nanocarriers

2016

This is the peer reviewed version of the following article: Vegas, V. G., Lorca, R., Latorre, A., Hassanein, K., Gómez‐García, C. J., Castillo, O., ... & Amo‐Ochoa, P. (2017). Copper (II)–Thymine Coordination Polymer Nanoribbons as Potential Oligonucleotide Nanocarriers. Angewandte Chemie International Edition, 56(4), 987-991, which has been published in final form at https://doi.org/10.1002/anie.201609031. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions

Coordination polymerInorganic chemistrySupramolecular chemistryOligonucleotideschemistry.chemical_element02 engineering and technology010402 general chemistry01 natural sciencesCatalysischemistry.chemical_compoundColloidchemistry.chemical_classificationOligonucleotideNanoribbonsGeneral MedicineGeneral ChemistryPolymerQuímica021001 nanoscience & nanotechnologyCombinatorial chemistryCopper0104 chemical sciencesThymineCoordination polymerschemistryNanocarriers0210 nano-technologyNanocarriers
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A bioinspired metal–organic approach to cross-linked functional 3D nanofibrous hydro- and aero-gels with effective mixture separation of nucleobases …

2020

The direct reaction between Cu(CH3COO)2 and uracil-1-acetic acid in water gives rise to the formation of a hydrogel consisting of entangled nanometric ribbons of a crystalline antiferromagnetic 1D Cu(ii) coordination polymer (CP) decorated with biocompatible uracil nucleobases. This hydrogel is the precursor for the preparation of a meso/macroporous ultralight aerogel that shows a remarkable Young's modulus. As a proof-of-concept of the molecular recognition capability of the terminal uracil moieties anchored at Cu(ii) CP chains, this material has been tested as the selective stationary phase for the separation of nucleobase derivatives in HPLC columns.

PolymersCoordination polymerNanofibersHydrogelsAerogelUracil02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesHigh-performance liquid chromatography0104 chemical sciencesNucleobaseMetalchemistry.chemical_compoundMolecular recognitionchemistryChemical engineeringMetalsvisual_artvisual_art.visual_art_mediumGeneral Materials ScienceDirect reaction0210 nano-technologyCopperNanoscale
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Direct formation of Sub-Micron and Nanoparticles of a bioinspired coordination polymer based on Copper with Adenine

2017

We report on the use of different reaction conditions, e.g., temperature, time, and/or concentration of reactants, to gain control over the particle formation of a bioinspired coordination polymer based on copper(II) and adenine, allowing homogeneous particle production from microto submicro-, and up to nano-size. Additionally, studies on this reaction carried out in the presence of different surfactants gives rise to the control of the particle size due to the modulation of the electrostatic interactions. Stability of the water suspensions obtained within the time and pH has been evaluated. We have also studied that there is no significant effect of the size reduction in the magnetic prope…

Materials sciencePolymers and PlasticsCoordination polymerSurfactantsInorganic chemistryNanoparticlechemistry.chemical_element010402 general chemistry01 natural sciencesArticlesurfactantslcsh:QD241-441coordination polymers; surfactants; nanoparticleschemistry.chemical_compoundlcsh:Organic chemistryReaction conditions010405 organic chemistryGeneral ChemistryQuímicaElectrostaticsCopper0104 chemical sciencesCoordination polymerscoordination polymerschemistryHomogeneousParticleNanoparticlesnanoparticlesParticle size
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Multifunctional coordination polymers based on copper with modified nucleobases, easily modulated in size and conductivity.

2019

This Accepted Manuscript will be available for reuse under a CC BY-NC-ND licence after 24 months of embargo period

Models MolecularNanoprocessingCoordination polymerPolymersSupramolecular chemistrychemistry.chemical_elementConductivity010402 general chemistry01 natural sciencesBiochemistryOxalateNucleobaseInorganic Chemistrychemistry.chemical_compoundBipyridineCoordination ComplexesCoordination polymerNucleobasesMolecular Structure010405 organic chemistryChemistryHydrogen bondQuímicaCopperMagnetic and electrical properties0104 chemical sciencesCrystallographyCopperJournal of inorganic biochemistry
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CCDC 2064123: Experimental Crystal Structure Determination

2021

Related Article: Verónica G. Vegas, Ana Latorre, María Luisa Marcos, Carlos J. Gómez-García, Óscar Castillo, Félix Zamora, Jacobo Gómez, José Martínez-Costas, Miguel Vázquez López, Álvaro Somoza, Pilar Amo-Ochoa|2021|ACS Applied Materials and Interfaces|13|31|doi:10.1021/acsami.1c11612

Space GroupCrystallographycatena-[(mu-44'-bipyridine)-(mu-5-fluorouracil-1-acetato)-aqua-(5-fluorouracil-1-acetato)-copper(ii) hydrate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1934515: Experimental Crystal Structure Determination

2019

Related Article: Verónica G. Vegas, Noelia Maldonado, Oscar Castillo, Carlos J. Gómez-García, Pilar Amo-Ochoa|2019|J.Inorg.Biochem.|200|110805|doi:10.1016/j.jinorgbio.2019.110805

Space GroupCrystallographyCrystal SystemCrystal Structurecatena-[(mu-44'-bipyridine)-bis(mu-thymine-1-acetato)-di-copper(i)]Cell ParametersExperimental 3D Coordinates
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CCDC 1934514: Experimental Crystal Structure Determination

2019

Related Article: Verónica G. Vegas, Noelia Maldonado, Oscar Castillo, Carlos J. Gómez-García, Pilar Amo-Ochoa|2019|J.Inorg.Biochem.|200|110805|doi:10.1016/j.jinorgbio.2019.110805

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterscatena-[(mu-44'-bipyridine)-(mu-oxalato)-bis(mu-uracil-1-acetato)-di-copper(ii) dihydrate]Experimental 3D Coordinates
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CCDC 1934513: Experimental Crystal Structure Determination

2019

Related Article: Verónica G. Vegas, Noelia Maldonado, Oscar Castillo, Carlos J. Gómez-García, Pilar Amo-Ochoa|2019|J.Inorg.Biochem.|200|110805|doi:10.1016/j.jinorgbio.2019.110805

Space GroupCrystallographycatena-[(mu-44'-bipyridine)-(mu-oxalato)-bis(mu-thymine-1-acetato)-di-copper(ii) tetrahydrate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2064122: Experimental Crystal Structure Determination

2021

Related Article: Verónica G. Vegas, Ana Latorre, María Luisa Marcos, Carlos J. Gómez-García, Óscar Castillo, Félix Zamora, Jacobo Gómez, José Martínez-Costas, Miguel Vázquez López, Álvaro Somoza, Pilar Amo-Ochoa|2021|ACS Applied Materials and Interfaces|13|31|doi:10.1021/acsami.1c11612

Space GroupCrystallographyCrystal Systemcatena-[(mu-44'-bipyridine)-(mu-uracil-1-acetato)-aqua-(uracil-1-acetato)-copper(ii) trihydrate]Crystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1496195: Experimental Crystal Structure Determination

2017

Related Article: Verónica G. Vegas, Romina Lorca, Ana Latorre, Khaled Hassanein, Carlos J. Gómez-García, Oscar Castillo, Álvaro Somoza, Félix Zamora, Pilar Amo-Ochoa|2017|Angew.Chem.,Int.Ed.|56|987|doi:10.1002/anie.201609031

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterscatena-[aqua-(mu-44'-bipyridine)-bis((5-methyl-24-dioxo-34-dihydropyrimidin-1(2H)-yl)acetato)-copper(ii) dihydrate]Experimental 3D Coordinates
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