0000000000188897

AUTHOR

José A López-lópez

showing 8 related works from this author

Management of oral Graft versus Host Disease with topical agents: a systematic review

2015

Background: Oral Graft-versus-Host Disease (oGvHD) is a common complication of haematopoietic stem cell transplantation. Choosing the right topical application to be used intra orally can be a challenge. Consequently, the aim of this work is to review the effectiveness and safety of topical agents currently used in the management of the inflammatory mucosal lesions encountered in oGVHD. Material and Methods: We carried out electronic searches of publications up to May 2015 of the databases Pubmed, National Library of Medicine’s Medline, Embase and the Cochrane Central Register of Controlled Clinical trials to identify potentially relevant studies (keywords: “oral”, “graft”, “versus”, “host”…

medicine.medical_specialtyAdministration TopicalGraft vs Host DiseaseOdontologíaReviewDisease03 medical and health sciences0302 clinical medicinemedicineHumansIntensive care medicineGlucocorticoidsGeneral Dentistrybusiness.industryMucosal lesions030206 dentistryMedically compromised patients in Dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludSurgeryTransplantationGraft-versus-host diseaseOtorhinolaryngologyTopical agents030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASSurgeryStem cellMouth DiseasesbusinessComplicationImmunosuppressive Agents
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A pioneering epidemiological study investigating the incidence of squamous cell carcinoma of tongue in a Portuguese population

2012

Objective: The purpose of this study was to investigate the incidence of squamous cell carcinoma (SCC) of the anterior two thirds of the tongue in a population living in central and southern Portugal, all treated at Portuguese Institute of Oncology of Lisbon, Francisco Gentil (IPOLFG). Study Design: This study was a retrospective review of all patients who had a histopathological diagnosis of SCC of the anterior two thirds of the tongue and had been treated in the Head and Neck Surgery Unit at the IPOLFG (Lisbon, Portugal), between 1st January 2001 and 31st December 2009. The risk factors evaluated were: gender; age; alcohol consumption; tobacco use; prosthesis use and the carcinoma site. R…

AdultMalemedicine.medical_specialtyCancer cellsPopulationYoung AdultTongueEpidemiologyCarcinomamedicineHumansTongue NeoplasmeducationGeneral DentistryAgedRetrospective StudiesAged 80 and overMoutheducation.field_of_studyOral Medicine and PathologyPortugalPortuguesebusiness.industryIncidenceBocaIncidence (epidemiology)Retrospective cohort studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseTongue NeoplasmsPortuguesosSurgerymedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellEtiologyResearch-ArticleFemaleCèl·lules cancerosesSurgerybusinessDemographyMedicina Oral Patología Oral y Cirugia Bucal
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Diagonal ear lobe crease and atherosclerosis : a review of the medical literature and dental implications

2011

In Spain a significant number of individuals die from atherosclerotic disease of the coronary and carotid arteries without having classic risk factors and prodromal symptoms. The diagonal ear lobe crease (DELC) has been characterized in the medical literature as a surrogate marker which can identify high risk patients having occult atherosclerosis. This topic however has not been examined in either the medical or dental literature emanating from Spain. The majority of clinical, angiography and postmortem reports support the premise that DELC is a valuable extravascular physical sign able to distinguish some patients at risk of succumbing to atherosclerosis of the coronary arteries. A minori…

AgingArteriosclerosisGerodontologypanoramic radiographsCoronary Artery DiseaseCardiovascularCoronary artery diseaseCoronary diseasesatherosclerosis diseaseEar Externalmedicine.diagnostic_testStomatognathic DiseasesEar:CIENCIAS MÉDICAS [UNESCO]Heart Diseasemedicine.anatomical_structureOrellaUNESCO::CIENCIAS MÉDICASRadiologyRadiologia dentalcalcified carotid arterymedicine.medical_specialtyPanoramic radiographVital signsArteriosclerosiMalalties coronàriesPanoramicRadiography PanoramicDiagonal ear lobe creasemedicineotorhinolaryngologic diseasesHumansMedical historyEspanyaDental/Oral and Craniofacial DiseaseGeneral DentistryHeart Disease - Coronary Heart DiseaseSurrogate endpointbusiness.industryPreventionReview-ArticleDental radiologyatheromasAtherosclerosismedicine.diseaseOccultExternalRadiographyCoronary arteriesArterioesclerosiOtorhinolaryngologySpainDentistryAngiographySurgerybusiness
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Incidence rate of metastases in the oral cavity: a review of all metastatic lesions in the oral cavity

2021

Background Metastases in the oral cavity are rare and account for only 1 to 3% of all malignant lesions in this area. The primary location from which most metastases have been described in the oral cavity in adult patients include lungs, breasts, kidneys and colon. Material and Methods A systematic search of the literature was carried out following the PRISMA statement in PubMed database. Clinical trials and case series published in the last 10 years [2010-2020] were eligible to be selected. The headings and keywords used in the searches were “cancer” AND “oral metastases”, “incidence” AND “oral metastases”, “oral metastases” AND “jaw bone”, “oral metastases” AND “soft tissue”. Results For …

AdultMalepleomorphic adenomamedicine.medical_specialtyReviewMetastasisMetàstasiProstateOral Cancer and Potentially malignant disorderssublingual glandHumansMedicineadenoid cystic carcinomaGeneral DentistryUNESCO:CIENCIAS MÉDICASRetrospective Studiesbusiness.industryOral cancerIncidenceIncidence (epidemiology)ThyroidSoft tissueCancerRetrospective cohort studymedicine.diseasePrimary tumorCàncer de bocamucoepidermoid carcinomaClinical trialsalivary gland neoplasmsmedicine.anatomical_structureJawOtorhinolaryngologyMouth NeoplasmsSurgeryRadiologybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Medication-related osteonecrosis of the jaw associated with implant and regenerative treatments : systematic review

2019

Background The aim of this study was to determine if the treatment with bisphosphonates other anti-resorptive and antiangiogenic agents influences the success of regenerative and / or implant treatments. Material and Methods We reviewed the literature from the last 5 years in the PubMed database, using the following words: “Sinus Floor Augmentation”[Mesh] OR “Dental Implants”[Mesh]) OR “Guided Tissue Regeneration”[Mesh]) AND “Osteonecrosis”[Mesh]. The articles were selected following the inclusion and exclusion criteria and were evaluated using the 22 items of the STROBE declaration. The following PICO clinical question was applied: Does the treatment with agents associated with drug osteon…

Dental Restoration FailureSinus Floor AugmentationBone RegenerationDatabases FactualMEDLINESinus Floor AugmentationDentistryReviewRessenyes sistemàtiques (Investigació mèdica)law.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawSystematic reviews (Medical research)medicineOssosAnimalsHumansDental Restoration FailureMethodological qualityGeneral DentistryDental ImplantsBonesDiphosphonatesImplants dentalsbusiness.industryDental Implantation EndosseousDental implantsOsteonecrosisAntibodies Monoclonal030206 dentistryMedically compromised patients in Dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]OtorhinolaryngologyEfectes secundaris dels medicamentsInclusion and exclusion criteriaUNESCO::CIENCIAS MÉDICASDrug side effectsSurgeryImplantbusinessOsteonecrosis of the jawDrug Antagonism
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A comparison of the dental status and treatment needs of older adults with and without chronic mental illness in Sevilla, Spain

2012

Objectives: To study the dental status and treatment needs of institutionalized older adults with chronic mental illness compared to a non-psychiatric control sample. Study Design: The sample size was 100, in which 50 were psychogeriatric patients (study group; SG) classified according to DSM-IV, with a mean age of 69.6 ± 6.7 years, and 50 non-psychiatric patients (control group; CG), with a mean age of 68.3 ± 6.9 years. Clinical oral health examinations were conducted and caries were recorded clinically using the Decayed, Missing and Filled Teeth Index (DMFT). Results were analyzed statistically using the Student’s t-test or analysis of variance. Results: Caries prevalence was 58% and 62% …

MaleDecayed teethCross-sectional studyGerodontologyDentistryOral HealthOdontologíaGeriatric dentistryOral healthDental Care for Agedstomatognathic systemHumansMedicineGeneral DentistryAgedHealth Services Needs and DemandImplants dentalsbusiness.industryMental DisordersDMFT IndexDental implants:CIENCIAS MÉDICAS [UNESCO]Dental careCiencias de la saludstomatognathic diseasesCross-Sectional StudiesOtorhinolaryngologySpainSample size determinationChronic mental illnessMental illnessChronic DiseaseUNESCO::CIENCIAS MÉDICASDental Care for AgedSchizophreniaResearch-ArticleFemaleSurgeryEsquizofrèniaOdontologia geriàtricabusinessMalalties mentals
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Correlation between periodontal disease management and metabolic control of type 2 diabetes mellitus: a systematic literature review

2016

Background: Diabetes and periodontal disease share common features in terms of inflammatory responses. Current scientific evidence suggests that treatment of periodontal disease might contribute to glycemic control. The objective of the study is a review of the last three years. Material and Methods: A literature search was performed in the MEDLINE (PubMed), Cochrane, and Scopus databases, for articles published between 01-01-2013 and 30-06-2015, applying the key terms “periodontal disease” AND “diabetes mellitus”. The review analyzed clinical trials of humans published in English and Spanish. Results: Thirteen clinical trials were reviewed, representing a total of 1,912 patients. Three of …

Blood Glucosemedicine.medical_specialtyPathologyMEDLINEOdontologíaReviewMalalties periodontals03 medical and health sciences0302 clinical medicineDiabetes mellitusInternal medicinemedicineHumans030212 general & internal medicineGeneral DentistryPeriodontal DiseasesGlycemicGlycated HemoglobinClinical Trials as TopicOral Medicine and PathologyDiabetisbusiness.industryDiabetesType 2 Diabetes Mellitus030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludJadad scaleClinical trialSystematic reviewGlucoseOtorhinolaryngologyDiabetes Mellitus Type 2Metabolic control analysisUNESCO::CIENCIAS MÉDICASGlucosaSurgeryPeriodontal diseasebusiness
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Coffee is protective against oral and pharyngeal cancer: A systematic review and meta-analysis

2017

Objectives: Certain Coffee is one of the most popular and consumable drinks worldwide. However, there are conflicting results on the influence of this drink in oral and pharyngeal cancer risk. To clarify this, we aimed to systemically review and carry out a meta-analysis of the relevant literature on the association between coffee and oral and pharyngeal cancer. Study Design: We carried out an electronic search of publications up to August 2016 from PubMed, National Library of Medicines Medline, Embase, Science Direct and the Cochrane Central Register. The Newcastle–Ottawa scale was used to address the quality of the studies a meta-analysis was carried out using random-effects models. Resul…

medicine.medical_specialtyMEDLINEDentistryReviewCoffee03 medical and health sciencesCoffee drink0302 clinical medicineCaffeinePharyngeal cancerInternal medicinemedicineHumansGeneral DentistryUNESCO:CIENCIAS MÉDICASMouth neoplasmOral Medicine and Pathologybusiness.industryOral cancerPharyngeal Neoplasms030206 dentistryPublication biasCàncer de bocaCafè (Beguda)Meta-analysisPharyngeal NeoplasmOtorhinolaryngologyCafeïna030220 oncology & carcinogenesisMeta-analysisSurgeryObservational studyMouth NeoplasmsbusinessMetaanàlisiCohort studyMedicina Oral, Patología Oral y Cirugía Bucal
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