0000000000190358

AUTHOR

Christian Weimar

showing 4 related works from this author

Associations of long-term exposure to air pollution and road traffic noise with cognitive function : an analysis of effect measure modification

2017

Background: Adverse effects of traffic-related air pollution (AP) and noise on cognitive functions have been proposed, but little is known about their interactions and the combined effect of co-exposure. Methods: Cognitive assessment was completed by 4086 participants of the population-based Heinz Nixdorf Recall cohort study using five neuropsychological subtests and an additively calculated global cognitive score (GCS). We assessed long-term residential concentrations for size-fractioned particulate matter (PM) and nitrogen oxides with land use regression. Road traffic noise (weighted 24-h (LDEN) and night-time (LNIGHT) means) was assessed according to the EU directive 2002/49/EC. Linear r…

MaleMeteorologyPopulationMedizin010501 environmental sciences01 natural sciences03 medical and health sciences0302 clinical medicineCognitionInterquartile rangeAir PollutionStatisticsLinear regressionMedicineHumansProspective Studieseducationlcsh:Environmental sciences0105 earth and related environmental sciencesGeneral Environmental ScienceAgedlcsh:GE1-350education.field_of_studyAir Pollutantsbusiness.industryTraffic noiseNeuropsychologyCognitionEnvironmental ExposureMiddle AgedConfidence intervalNoiseNoise TransportationHousingLinear ModelsFemaleNitrogen OxidesParticulate Matterbusiness030217 neurology & neurosurgery
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The role of depressive symptoms within the association of long-term exposure to indoor and outdoor traffic noise and cognitive function – Results fro…

2019

Abstract Objectives Traffic noise is negatively associated with cognitive function, and its perception can differ between depressed and non-depressed people. We studied the role of depressive symptoms in the association between traffic noise and cognitive function. We studied the role of depressive symptoms in the association between traffic noise and cognitive function. Methods During the first follow-up examination (2006–2008) of the German Heinz Nixdorf Recall study, cognitive function (five subtests and an additive global summary score, GCS) and depressive symptoms (CES-D score) were assessed in 2745 participants (aged 50–80, 49.8% women). Mild cognitive impairment (MCI) was diagnosed a…

Malemedicine.medical_specialtyMedizin010501 environmental sciencesAudiologyLogistic regression01 natural sciences03 medical and health sciencesCognition0302 clinical medicinemedicineHumansVerbal fluency testCognitive Dysfunction030212 general & internal medicineAssociation (psychology)Depression (differential diagnoses)0105 earth and related environmental sciencesRecallDepressionbusiness.industryTraffic noisePublic Health Environmental and Occupational HealthCognitionEnvironmental ExposureNoiseNoise TransportationFemalebusinessInternational Journal of Hygiene and Environmental Health
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Abstract TMP17: Revacept, an Inhibitor of Platelet Adhesion in Patients With Symptomatic Carotid Artery Stenosis. Safety Data From the International …

2020

Introduction: Revacept is a novel vascular lesion-directed inhibitor of platelet adhesion and thrombus formation, exhibiting no effects on the homeostatic functions of circulating platelets. Objective: The effects of Revacept on plaque-mediated thrombosis were investigated in patients with symptomatic stenosis of the internal carotid artery (at least 50%, following ECST-criteria). Methods: Within an international, prospective, multicenter (n=16), randomized trial 158 patients could be randomized to receive placebo, or 40/120 mg Revacept by intravenous infusion over 20 minutes. Cerebrovascular events and cardiovascular complications were followed up to 3 months. Results: 158 patients were f…

Advanced and Specialized Nursingmedicine.medical_specialtybusiness.industryPlatelet adhesionmedicine.medical_treatmentSymptomatic carotid artery stenosisPhases of clinical researchStentCarotid endarterectomymedicine.diseaseInternal medicinemedicineCardiologyPlateletIn patientNeurology (clinical)ThrombusCardiology and Cardiovascular MedicinebusinessStroke
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Safety of endovascular treatment in acute stroke patients taking oral anticoagulants

2017

International journal of stroke 12(4), 412-415 (2017). doi:10.1177/1747493016677986

Maletherapeutic use [Anticoagulants]medicine.medical_specialtyMedizinAdministration Oral030204 cardiovascular system & hematologyBrain IschemiaBrain ischemia03 medical and health sciences0302 clinical medicineetiology [Intracranial Hemorrhages]Modified Rankin ScaleInterquartile rangeAntithromboticmedicineHumansThrombolytic Therapyddc:610Prospective StudiesRegistriesadverse effects [Anticoagulants]Prospective cohort studyStrokeAgedAged 80 and overbusiness.industryConfoundingAnticoagulantsmethods [Thrombolytic Therapy]complications [Brain Ischemia]Middle Agedmedicine.diseasedrug therapy [Stroke]Surgerysurgery [Stroke]StrokeTreatment Outcomeadministration & dosage [Anticoagulants]Neurologydrug therapy [Brain Ischemia]FemaleObservational studydrug therapy [Intracranial Hemorrhages]businessIntracranial Hemorrhages030217 neurology & neurosurgery
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