0000000000192786

AUTHOR

S. Conoci

showing 4 related works from this author

Alcoxy-substituted conjugated polymers and oligomers for chemical and bio-sensing Langmuir-Schafer thin film transistors

2005

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Alkoxy substituted conjugated polymer Langmuir-Shaefer thin films transistors for chemical and bio-sensing

2005

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Poly(alkoxy-phenylenethienylene) Langmuir-Schäfer thin-film for advanced performance in electronic devices

2005

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SiPM as miniaturised optical biosensor for DNA-microarray applications

2015

A miniaturized optical biosensor for low-level fluorescence emitted by DNA strands labelled with CY5 is showed. Aim of this work is to demonstrate that a Si-based photodetector, having a low noise and a high sensitivity, can replace traditional detection systems in DNA-microarray applications. The photodetector used is a photomultiplier (SiPM), with 25 pixels. It exhibits a higher sensitivity than commercial optical readers and we experimentally found a detection limit for spotted dried samples of ∼1 nM. We measured the fluorescence signal in different operating conditions (angle of analysis, fluorophores concentrations, solution volumes and support). Once fixed the angle of analysis, for s…

Detection limitAnalytePhotomultiplierMaterials scienceoptical biosensorbusiness.industrySiPMDNA microarrayPhotodetectorLinearityDNA-microarraySignalSettore ING-INF/01 - ElettronicaElectronic Optical and Magnetic MaterialsSilicon photomultiplierOpticslcsh:TA1-2040DNA microarray; Fluorophore detection; Optical Biosensor; SiPMSignal ProcessingElectrical and Electronic Engineeringbusinesslcsh:Engineering (General). Civil engineering (General)Sensitivity (electronics)Fluorophore detectionBiotechnologySensing and Bio-Sensing Research
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