0000000000193969

AUTHOR

Jens Laurits Larsen

showing 4 related works from this author

Vibrio vulnificus produces quorum sensing signals of the AHL-class

2009

Vibrio vulnificus is an aquatic pathogenic bacterium that can cause vibriosis in humans and fish. The species is subdivided into three biotypes with the fishvirulent strains belonging to biotype 2. The quorum sensing (QS) phenomenon mediated by furanosyl borate diester or autoinducer 2 (AI-2) has been described in human strains of biotype 1, and here we show that the luxS gene which encodes AI-2 is present in all strains of V. vulnificus regardless of origin, biotype or serovar.In this study, we also demonstrate that V. vulnificus produces QS signals of the acylated homoserine lactone (AHL) class (AI-1). AHLs were detected in strains of biotype 1 and 2 from water, fish and human wound infec…

food and beveragesMicrobiologiabiochemical phenomena metabolism and nutrition
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Vibrio vulnificus produces quorum sensing signals of the AHL-class

2009

Vibrio vulnificus is an aquatic pathogenic bacterium that can cause vibriosis in humans and fish. The species is subdivided into three biotypes with the fish-virulent strains belonging to biotype 2. The quorum sensing (QS) phenomenon mediated by furanosyl borate diester or autoinducer 2 (AI-2) has been described in human strains of biotype 1, and here we show that the luxS gene which encodes AI-2 is present in all strains of V. vulnificus regardless of origin, biotype or serovar. In this study, we also demonstrate that V. vulnificus produces QS signals of the acylated homoserine lactone (AHL) class (AI-1). AHLs were detected in strains of biotype 1 and 2 from water, fish and human wound inf…

EcologyHomoserinefood and beveragesVibrio vulnificusbiochemical phenomena metabolism and nutritionBiologybiology.organism_classificationApplied Microbiology and BiotechnologyMicrobiologyTryptic soy brothAutoinducer-2Microbiologychemistry.chemical_compoundQuorum sensingchemistryVibrionaceaeVibrio InfectionsBacteriaFEMS Microbiology Ecology
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Field testing of a vaccine against eel diseases caused by Vibrio vulnificus

2001

The field results of a vaccination programme against Vibrio vulnificus serovar E (biotype 2) in a Spanish eel farm are reported. A total of 9.5 million glass eels were vaccinated from January 1998 to March 2000 by prolonged immersion followed by 2 subsequent reimmunisations after 12 to 14 and 24 to 28 d, respectively. The acquired protection and the immune response against serovar E were estimated over a period of 6 mo after vaccination. A similar vaccination schedule was conducted with elvers in a Danish eel farm. In this case, the acquired protection and the immune response against serovar E and the new eel-pathogenic serovars, recently described in Denmark, were evaluated over a short te…

Serotypeendocrine systemTime Factorsanimal structuresVaccination scheduleField vaccination. vibriosisVibrio vulnificus biotype 2Eel vaccinesVibrio vulnificusAquatic Science:CIENCIAS DE LA VIDA [UNESCO]MicrobiologyFish DiseasesImmune systemVibrionaceaeAnguillidaeUNESCO::CIENCIAS DE LA VIDAAnimalsUNESCO::CIENCIAS DE LA VIDA::Biología animal (Zoología)Vibrio vaccinesEcology Evolution Behavior and SystematicsVaccination by prolonged immersionVibrioEels:CIENCIAS DE LA VIDA::Biología animal (Zoología) [UNESCO]biologyVibrio vulnificus serovar E ; Vibrio vulnificus biotype 2 ; Eel vaccines ; Vibrio vaccines ; Vaccination by prolonged immersion ; Field vaccination. vibriosisBody WeightVaccinationbiology.organism_classificationAntibodies BacterialVaccinationVibrio vulnificus serovar EVibrio InfectionsHumoral immunityBacterial Vaccines
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Vibrio vulnificus serovar A: an emerging pathogen in European anguilliculture.

2006

The spread of the emerging pathogen Vibrio vulnificus biotype 2 serovar A in Danish anguilliculture is reported. Serovar A was originally isolated in a Spanish eel farm in 2000 and occurred in Denmark in the summer of 2004, affecting eels of 5-10 g body weight cultured in fresh water. The Danish eels showed clinical signs different from those reported for Spanish eels, such as severe haemorrhages in the head and gill region with necrosis of the soft tissues. Danish isolates were biochemically and serologically identical to Spanish serovar A strains and also highly virulent for eels by both intraperitoneal injection and immersion challenges. Vaccination with Vulnivaccine, a vaccine against V…

Serotypeendocrine systemanimal structuresVeterinary (miscellaneous)DenmarkFisheriesVirulenceVibrio vulnificusMicrobial Sensitivity TestsAquatic ScienceBody weightCommunicable Diseases EmergingMicrobiologyDisease OutbreaksEmerging pathogenFish DiseasesAnimalsSerotypingVibrio vulnificusVibrioEelsbiologyVirulenceVaccinationbiology.organism_classificationVirologyVaccinationFresh waterVibrio InfectionsBacterial VaccinesJournal of fish diseases
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