0000000000194171

AUTHOR

Pavel Leahu

showing 2 related works from this author

Multifocal Repetitive Transcranial Magnetic Stimulation—A Novel Paradigm in Migraine Treatment

2019

Transcranial Magnetic Stimulation (TMS) is a non-invasive brain stimulation method used for analyzing structural and functional interactions in brain, assess cortical reactivity, and map functionally relevant brain regions inducing a controlled current pulse in a defined region of the cortex. From a clinical point of view, TMS has shown promising results in the therapeutic approach in a large number of psychiatric and neurological conditions such as anxiety, depression, OCD, headache disorders—migraine being one of the most encountered, etc. In patients with migraine, the pharmacologic therapy can be divided in abortive and preventive treatment of the attack. Usually the treatment is starte…

medicine.medical_specialtybusiness.industrymedicine.medical_treatmentStimulationmedicine.diseaseTranscranial magnetic stimulationTherapeutic approachPhysical medicine and rehabilitationMigraineBrain stimulationmedicineAnxietyMigraine treatmentmedicine.symptombusinessDepression (differential diagnoses)
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Increased migraine-free intervals with multifocal repetitive transcranial magnetic stimulation.

2021

Introduction: Episodic migraine is a debilitating condition associated with vast impairments of health, daily living, and life quality. Several prophylactic treatments exist, having a moderate ratio of action related to side effects and therapy costs. Repetitive transcranial magnetic stimulation (rTMS) is an evidence based therapy in several neuropsychiatric conditions, showing robust efficacy in alleviating specific symptoms. However, its efficacy in migraine disorders is unequivocal and might be tightly linked to the applied rTMS protocol. We hypothesized that multifocal rTMS paradigm could improve clinical outcomes in patients with episodic migraine by reducing the number of migraine day…

AdultAuramedicine.medical_treatmentMigraine Disorders50% responder RatesBiophysicsStimulationNeurosciences. Biological psychiatry. NeuropsychiatryPilot Projectslaw.inventionRandomized controlled trialDouble-Blind MethodlawmedicineHumansAdverse effectMigraineBalance (ability)business.industryGeneral NeurosciencePreventionMiddle Agedmedicine.diseaseTranscranial Magnetic StimulationTranscranial magnetic stimulationMultifocal rTMSTreatment OutcomeMigraineAnesthesiaPropensity score matchingMigraine daysQuality of LifeFemaleNeurology (clinical)businessRC321-571Brain stimulation
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