0000000000195084

AUTHOR

Silvia Menendez-cepero

showing 2 related works from this author

Importance of the toxicological tests in the application and safety of ozone therapy

2018

Until today, there is not any official registry of the different routes of systemic ozone therapy. With the aim to prove the safety of this therapy, several ways of ozone (O3) applications were evaluated, such as rectal insufflation (RI), major autohemotherapy (M-AHT) and intraperitoneal application (IP). For RI, some toxicological tests were performed such as: acute, sub-chronic, mutagenic (bone marrow chromosomic aberrations and micronucleus), teratogenic  and irritation studies (at 40 mg/L and 10 mL during 15 days). For M-AHT, acute toxicological (in rats with 21, 47 and 64 mg/L and a volume of 2 mL with daily evaluation up to 15 days) and mutagenic (chromosomal aberration analysis, micr…

business.industrySister chromatid exchangePharmacologymedicine.disease_causeOzone therapy:CIENCIAS MÉDICAS [UNESCO]AutohemotherapyClastogenMicronucleus testUNESCO::CIENCIAS MÉDICASmedicineIrritationbusinessMicronucleus
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Clinical behavior of children with infantile cerebral palsy after ozone therapy

2018

Objective.
 The aim of this study was to determine the usefulness of ozone therapy in the treatment of Infantile Cerebral Palsy (ICP). 
 
 Patients and methods.
 A non-controlled clinical assay was made in the Ozone Research Center (CIO), Havana, Cuba from January 2013 to January 2014. The sample was constituted by patients remitted to pediatrics consultation of CIO, to whom inclusion and exclusion criteria were applied. The study group involved 45 patients, from 1 month of birth to 8 years, with cerebral palsy of hypoxic-ischemic cause. The evaluation criteria were: evolution of the motor disorder according to the Gross Motor Function Classification System (GMFCS) scale…

Motor disorderPediatricsmedicine.medical_specialtybusiness.industryGross Motor Function Classification SystemOzone therapymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Response to treatmentCerebral palsyMuscle tonemedicine.anatomical_structureInclusion and exclusion criteriaUNESCO::CIENCIAS MÉDICASmedicinebusinessInfantile cerebral palsy
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