0000000000195347

AUTHOR

Ingemar Kåreholt

showing 4 related works from this author

Association between mid- to late life physical fitness and dementia: Evidence from the CAIDE study

2014

Objectives. This study investigated the association between perceived physical fitness at midlife, changes in perceived fitness during the three decades from mid-to late life and dementia risk. Design. Prospective cohort study. Setting. Cardiovascular risk factors, ageing and incidence of dementia (CAIDE) study. Subjects. Subjects were selected from four independent, random samples of population-based cardiovascular surveys and were first examined in 1972, 1977, 1982 or 1987, when they were on average 50 years old. The CAIDE target population included 3559 individuals. A random sample of 2000 individuals still alive in 1997 was drawn for re-examinations (performed in 1998 and 2005-2008) tha…

GerontologyMalePhysical fitnessPopulationApolipoprotein E4ta3112Internal MedicineMedicineDementiaHumansProspective StudiesSex DistributionProspective cohort studyeducationta315Agededucation.field_of_studybusiness.industryIncidence (epidemiology)Hazard ratiota3141Odds ratiota3142Middle Agedta3121medicine.diseaseConfidence intervalSelf ConceptPhysical FitnessDementiaFemaleSedentary BehaviorbusinessJournal of Internal Medicine
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Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia

2013

Abstract Background Physical activity may be beneficial for cognition, but the effect may vary depending on personal characteristics. Methods We investigated the associations between leisure-time physical activity (LTPA) from mid- to late life, the risk of dementia, and the role of body mass index, sex, and APOE in the CAIDE study during 28-year follow-up. Cognitive function of a random subsample was assessed at a mean age of 78.8 years (n = 1511), and dementia/Alzheimer's disease (AD) diagnoses were identified from national registers for the entire target population (n = 3559). Results Moderate (hazard ratio [HR], 1.46; 95% confidence interval [CI], 1.08–1.99) and low levels of midlife LTP…

GerontologyMaleEpidemiologyNeuroimagingOverweightMotor ActivityNeuropsychological TestsCommunity Health PlanningBody Mass IndexCellular and Molecular NeuroscienceLeisure ActivitiesDevelopmental NeuroscienceRisk FactorsmedicineDementiaHumansLongitudinal StudiesObesityExerciseFinlandAgedProportional Hazards Models2. Zero hungerAged 80 and overPsychiatric Status Rating ScalesPhysical activityHealth PolicyHazard ratioAge FactorsLife courseta3142Middle Agedmedicine.diseaseObesityConfidence interval3. Good healthPsychiatry and Mental healthDisease ProgressionLife course approachFemaleDementiaNeurology (clinical)Geriatrics and Gerontologymedicine.symptomPsychologyCohort studyBody mass indexCohort studyAlzheimers and Dementia
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P3‐315: MID‐LIFE WORK‐RELATED STRESS INCREASES DEMENTIA RISK IN LATE‐LIFE: THE CAIDE 30‐YEAR STUDY

2014

Background: The associations between work-related stress and various health outcomes in mid-life are well documented, yet less is known about the effects on late-life cognitive process and dementia. The current study investigated the associations between work-related stress in mid-life and the development of cognitive impairment and Alzheimer’s disease in late-life. Methods: The data was derived from the Cardiovascular Risk Factors, Aging, and Incidence of Dementia (CAIDE) study; a prospective cohort study. Participants were randomly selected from four independent population-based samples that completed cardiovascular surveys. First baseline examinations occurred when participants were 50 y…

Gerontologyeducation.field_of_studyEpidemiologybusiness.industryHealth PolicyPopulationNeuropsychologyLonelinessCognitionOdds ratiomedicine.diseaseConfidence intervalPsychiatry and Mental healthCellular and Molecular NeuroscienceDevelopmental NeuroscienceMedicineDementiaNeurology (clinical)Geriatrics and Gerontologymedicine.symptomProspective cohort studyeducationbusinessAlzheimer's & Dementia
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P2‐310: MIDLIFE SELF‐RATED HEALTH AND FITNESS IN RELATION TO WHITE MATTER LESIONS AND GREY MATTER VOLUME 20 YEARS LATER

2014

Midlife self-rated health and fitness in relation to white matter lesions and grey matter volume 20 years later

GerontologyEpidemiologybusiness.industryHealth PolicyGrey matterHyperintensityPsychiatry and Mental healthCellular and Molecular Neurosciencemedicine.anatomical_structureDevelopmental NeurosciencemedicineNeurology (clinical)Geriatrics and GerontologybusinessSelf-rated healthVolume (compression)Alzheimer's & Dementia
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