0000000000199572

AUTHOR

Bernard Berger

showing 4 related works from this author

Additional file 1 of Safety and efficacy of a probiotic-containing infant formula supplemented with 2���-fucosyllactose: a double-blind randomized co…

2022

Additional file 1.

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Additional file 2 of Safety and efficacy of a probiotic-containing infant formula supplemented with 2���-fucosyllactose: a double-blind randomized co…

2022

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Safety and efficacy of a probiotic-containing infant formula supplemented with 2'-fucosyllactose: a double-blind randomized controlled trial

2022

Abstract Background Human milk oligosaccharides (HMOs) have important and diverse biological functions in early life. This study tested the safety and efficacy of a starter infant formula containing Limosilactobacillus (L.) reuteri DSM 17938 and supplemented with 2’-fucosyllactose (2’FL). Methods Healthy infants < 14 days old (n = 289) were randomly assigned to a bovine milk-based formula containing L. reuteri DSM 17938 at 1 × 107 CFU/g (control group; CG) or the same formula with added 1.0 g/L 2’FL (experimental group; EG) until 6 months of age. A non-randomized breastfed group served as reference (BF; n = 60). The primary endpoint was weight gain through 4 months of age in the formula-…

Gut microbiomeNutrition and DieteticsMilk HumanProbioticsgrowthHuman milk oligosaccharidesMedicine (miscellaneous)InfantOligosaccharidesgut microbiomeinfant formulaGrowth2’fucosyllactose2’fucosyllactose Growth Gut microbiome Human milk oligosaccharides Infant formula2'fucosyllactoseFecesDouble-Blind MethodInfant formulaHumansPediatrics Perinatology and Child HealthTrisaccharidesPhylogeny
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Linking Human Milk Oligosaccharides, Infant Fecal Community Types, and Later Risk To Require Antibiotics

2020

Human milk is the sole and recommended nutrition for the newborn infant and contains one of the largest constituents of diverse oligosaccharides, dubbed human milk oligosaccharides (HMOs). Preclinical and clinical association studies indicate that HMOs have multiple physiological functions largely mediated through the establishment of the gut microbiome. Until recently, HMOs were not available to investigate their role in randomized controlled intervention trials. To our knowledge, this is the first report on the effects of 2 HMOs on establishing microbiota in newborn infants. We provide a detailed description of the microbiota changes observed upon feeding a formula with 2 HMOs in comparis…

Malefecal community types030309 nutrition & dieteticsmedicine.drug_classLNnTAntibioticsPhysiologyOligosaccharidesGut floraformulaMicrobiologyantibioticsHost-Microbe Biology03 medical and health sciencesFecesfluids and secretionsDouble-Blind MethodVirologyRNA Ribosomal 16SmicrobiotaMedicineHumansFeceshealth care economics and organizations030304 developmental biologyBifidobacterium0303 health sciencesbiologyBacteriaMilk Humanbusiness.industryInfant Newbornbiology.organism_classificationinfantInfant Formula2′FLQR1-502Anti-Bacterial AgentsGastrointestinal MicrobiomeClinical trialBifidobacteriaceaeBreast FeedingInfant formulaEnterotypeFemalehuman milk oligosaccharidesBifidobacteriumbusinessResearch ArticlemBio
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