0000000000200108

AUTHOR

Nicoletta Protti

showing 7 related works from this author

Testing and linearity calibration of films of phenol compounds exposed to thermal neutron field for EPR dosimetry

2015

This paper reports the preliminary results obtained by Electron Paramagnetic Resonance (EPR) measurements on films of IRGANOX® 1076 phenols with and without low content (5% by weight) of gadolinium oxide (Gd2O3) exposed in the thermal column of the Triga Mark II reactor of LENA (Laboratorio Energia Nucleare Applicata) of Pavia (Italy). Thanks to their size, the phenolic films here presented are good devices for the dosimetry of beams with high dose gradient and which require accurate knowledge of the precise dose delivered. The dependence of EPR signal as function of neutron dose was investigated in the fluence range between 10(11) cm(-2) and 10(14) cm(-2). Linearity of EPR response was fou…

Settore ING-IND/20 - Misure E Strumentazione NucleariAnalytical chemistryGadoliniumFluenceTRIGAlaw.inventionNCT dosimetrychemistry.chemical_compoundPhenolslawCalibrationPhenolDosimetryIrradiationElectron paramagnetic resonanceNeutron beamNeutronsRadiationPhenolSettore ING-IND/18 - Fisica Dei Reattori NucleariSettore FIS/01 - Fisica SperimentaleElectron Spin Resonance SpectroscopyNeutron temperatureSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Electron Paramagnetic ResonancechemistryCalibrationNuclear chemistry
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Development of a 3D CZT Spectrometer System with Digital Readout for Hard X/Gamma-Ray Astronomy

2019

We report on the development and of a complete X/γ rays detection system (10-1000 keV) based on CZT spectrometers with spatial resolution in three dimensions (3D) and a digital electronics acquisition chain. The prototype is made by packing four linear modules, each composed of one 3D CZT sensors. Each sensors is realized using a single spectroscopic graded CZT crystal of about 20×20×5 mm3. An electrode structure consisting of 12 collecting anodes with a pitch of 1.6 mm and 3 drift strips between each pair of anodes for 48 strips (0.15 mm wide) on the anodic side was adopted. The cathode is made of 10 strips with a pitch of 2 mm and orthogonal to anode side strips. Since the reading of the …

Materials scienceSTRIPSCZT detectorsensorscomputer.software_genre01 natural scienceslaw.invention010309 opticsOpticslaw0103 physical sciencesDigital Readout010303 astronomy & astrophysicsImage resolutionDigital electronicsX-ray and gamma ray detectorsSpectrometerbusiness.industryFirmwareSettore FIS/01 - Fisica SperimentaleDetectorSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)CathodeAnode3D CZTbusinesscomputer2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)
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Neutron flux and gamma dose measurement in the BNCT irradiation facility at the TRIGA reactor of the University of Pavia

2018

Abstract University of Pavia is equipped with a TRIGA Mark II research nuclear reactor, operating at a maximum steady state power of 250 kW. It has been used for many years to support Boron Neutron Capture Therapy (BNCT) research. An irradiation facility was constructed inside the thermal column of the reactor to produce a sufficient thermal neutron flux with low epithermal and fast neutron components, and low gamma dose. In this irradiation position, the liver of two patients affected by hepatic metastases from colon carcinoma were irradiated after borated drug administration. The facility is currently used for cell cultures and small animal irradiation. Measurements campaigns have been ca…

inorganic chemicalsNuclear and High Energy PhysicsMaterials science030218 nuclear medicine & medical imagingTRIGAlaw.invention03 medical and health sciencesNeutron flux measurements Neutron activation Photon dosimetry Alanine dosimetry BNCT0302 clinical medicineAlanine dosimetry; BNCT; Neutron activation; Neutron flux measurements; Photon dosimetry; Nuclear and High Energy Physics; InstrumentationlawNeutron fluxNeutronInstrumentationPhoton dosimetryDosimeterRadiochemistrySettore FIS/01 - Fisica Sperimentaletechnology industry and agricultureNuclear reactorAlanine dosimetryNeutron temperatureSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Neutron captureNeutron flux measurements030220 oncology & carcinogenesisNeutron activationBNCTSettore MED/36 - Diagnostica Per Immagini E RadioterapiaNeutron activation
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Potentialities of High-Resolution 3-D CZT Drift Strip Detectors for Prompt Gamma-Ray Measurements in BNCT

2022

Recently, new high-resolution cadmium–zinc–telluride (CZT) drift strip detectors for room temperature gamma-ray spectroscopic imaging were developed by our group. The CZT detectors equipped with orthogonal anode/cathode collecting strips, drift strips and dedicated pulse processing allow a detection area of 6 × 20 mm2 and excellent room temperature spectroscopic performance (0.82% FWHM at 661.7 keV). In this work, we investigated the potentialities of these detectors for prompt gamma-ray spectroscopy (PGS) in boron neutron capture therapy (BNCT). The detectors, exploiting the measurement of the 478 keV prompt gamma rays emitted by 94% 7Li nuclides from the 10B(n, α)7…

Physics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaSettore FIS/01 - Fisica SperimentalePhysics::Medical PhysicsBNCT; CZT detectors; X-ray and gamma-ray detectorsBoron Neutron Capture TherapyCZT detectors; X-ray and gamma-ray detectors; BNCTBiochemistrySettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Atomic and Molecular Physics and OpticsAnalytical ChemistryZincX-ray and gamma-ray detectorsGamma RaysBNCTTelluriumElectrical and Electronic EngineeringInstrumentationCadmiumCZT detectors
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High performance 3D CZT spectro-imager for BNCT-SPECT: preliminary characterization

2018

The National Institute of Nuclear Physics (INFN) is supporting the 3CaTS project with the aim of developing a new Single Photon Emission Computed Tomography (SPECT) system for real time 10 B therapeutic dose monitoring in the binary experimental hadron therapy called Boron Neutron Capture Therapy (BNCT). BNCT is a highly selective tumour treatment based on the neutron capture reaction 10 B(n,α) 7 Li. The secondary particles have a high LET with ranges in tissues of the order of 10 μm (thus less than the mean cell diameter of few tens μm). Targeting the 10 B delivery towards cancer, the released energy lethally damages only the malignant cells sparing the normal tissues, thus enabling a cell…

Physicsmedicine.diagnostic_test010308 nuclear & particles physicsbusiness.industrySettore FIS/01 - Fisica SperimentaleDetectorResolution (electron density)Single-photon emission computed tomography01 natural sciencesSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)030218 nuclear medicine & medical imagingCharacterization (materials science)Hadron therapyBoron neutron capture therapy03 medical and health sciencesNeutron captureFull width at half maximum0302 clinical medicineOpticsSingle photon emission computed tomography.0103 physical sciencesmedicineNeutron irradiationbusinessX ray detector2018 IEEE Nuclear Science Symposium and Medical Imaging Conference Proceedings (NSS/MIC)
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New Results on High-Resolution 3-D CZT Drift Strip Detectors

2020

Intense research activities have been carry out in the development of room temperature gamma ray spectroscopic imagers, aiming to compete with the excellent energy resolution of high-purity germanium (HPGe) detectors (0.3 % FWHM at 662 keV) obtained after cryogenic cooling. Cadmium-zinc-telluride (CZT) detectors equipped with pixel, strip and virtual Frisch-grid electrode structures represented an appealing solution for room temperature measurements. In this work, we present the performance of new high-resolution CZT drift strip detectors (19.4 x 19.4 x 6 mm3), recently fabricated at IMEM-CNR of Parma (Italy) in collaboration with due2lab company (Reggio Emilia, Italy). The detectors, worki…

Materials scienceX-ray and gamma ray detectorsbusiness.industryDetectorSettore FIS/01 - Fisica SperimentaleGamma raychemistry.chemical_elementGermaniumCZT detectorTemperature measurementCathodeSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Semiconductor detectorlaw.inventionAnodeOpticsPlanarchemistrylawbusiness
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Recent advances in the development of high-resolution 3D cadmium-zinc-telluride drift strip detectors.

2020

In the last two decades, great efforts have been made in the development of 3D cadmium–zinc–telluride (CZT) detectors operating at room temperature for gamma-ray spectroscopic imaging. This work presents the spectroscopic performance of new high-resolution CZT drift strip detectors, recently developed at IMEM-CNR of Parma (Italy) in collaboration with due2lab (Italy). The detectors (19.4 mm × 19.4 mm × 6 mm) are organized into collecting anode strips (pitch of 1.6 mm) and drift strips (pitch of 0.4 mm) which are negatively biased to optimize electron charge collection. The cathode is divided into strips orthogonal to the anode strips with a pitch of 2 mm. Dedicated pulse processing analysis…

Nuclear and High Energy PhysicsMaterials sciencePhysics::Instrumentation and Detectors030303 biophysics3D CdZnTe detectorsSTRIPS01 natural sciencesElectric chargelaw.invention03 medical and health scienceschemistry.chemical_compounddrift strip detectorslaw0103 physical sciencesInstrumentation0303 health sciencesRadiation010308 nuclear & particles physicsbusiness.industryDetectorElectrostatic inductionSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)CathodeCadmium zinc tellurideAnodeFull width at half maximumX-ray and gamma-ray detectorschemistryX-ray and gamma-ray detectors; 3D CdZnTe detectors; drift strip detectors; spectroscopic X-ray and gamma-ray imagingOptoelectronicsbusinessspectroscopic X-ray and gamma-ray imagingJournal of synchrotron radiation
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