0000000000200117

AUTHOR

Shaoying Zhan

showing 3 related works from this author

Anti-hyperuricemic and nephroprotective effects of extracts from Chaenomeles sinensis (Thouin) Koehne in hyperuricemic mice

2018

Clinically, Chaenomeles sinensis (Thouin) Koehne (C. sinensis) has been used to treat hyperuricemia and gout. However, the exact mechanism of action is still unknown. In the present study, the ethyl acetate fraction of C. sinensis fruit extract (CSF-E) was separated. Potassium oxonate (PO)-induced hyperuricemic mice and normal mice were administered with CSF-E at 60, 120 and 180 mg kg-1, respectively for 7 days. Serum uric acid, creatinine and BUN levels, liver oxidative damage, and serum and hepatic XOD activities were primarily measured using assay kits. The evaluation of its nephroprotective effects was carried out by renal histopathological analysis. Simultaneously, renal protein levels…

Male0301 basic medicineXanthine OxidaseOrganic anion transporter 1PhytochemicalsOrganic Anion TransportersRenal functionHyperuricemiaPharmacologyurologic and male genital diseasesExcretionMice03 medical and health scienceschemistry.chemical_compoundOrganic Anion Transport Protein 1medicineAnimalsHyperuricemiaRosaceaeCreatinineKidneybiologyPlant ExtractsGeneral Medicinemedicine.diseaseUric AcidGoutDisease Models AnimalOxonic Acid030104 developmental biologymedicine.anatomical_structureGene Expression RegulationLiverchemistryCreatinineFruitbiology.proteinUric acidPhytotherapyFood ScienceFood & Function
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From ‘green’ technologies to ‘red’ antioxidant compounds extraction of purple corn: a combined ultrasound-ultrafiltration-purification approach

2018

A pilot scale process consisting of ultrasound-assisted extraction, ammonium sulfate precipitation, cross-flow ultrafiltration and AB-8 macroporous resins purification aiming to recover anthocyanins and zein from purple corn (PC) was optimized and scaled-up. The effects of five independent variables (ethanol concentration, liquid to solid ratio, ultrasound temperature, time and power) were discussed and the most influential factors were optimized.; Results: The highest total anthocyanin (0.45 ± 0.01 g kg-1 ) and zein (17.14 ± 1.73 g kg-1 ) contents from purple corn were obtained using an ultrasound power of 105 W, an extraction time of 90 min, an ethanol concentration of 74% and a liquid to…

Nutrition and DieteticsAntioxidantChromatographyEthanolmedicine.medical_treatment010401 analytical chemistryExtraction (chemistry)UltrafiltrationPurple corn04 agricultural and veterinary sciencesMass spectrometry040401 food science01 natural sciences0104 chemical scienceschemistry.chemical_compound0404 agricultural biotechnologychemistryAnthocyaninmedicineAgronomy and Crop ScienceAmmonium sulfate precipitationFood ScienceBiotechnologyJournal of the Science of Food and Agriculture
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Recovery of oil with unsaturated fatty acids and polyphenols from chaenomelessinensis (Thouin) Koehne: Process optimization of pilot-scale subcritica…

2017

The potential effects of three modern extraction technologies (cold-pressing, microwaves and subcritical fluids) on the recovery of oil from Chaenomelessinensis (Thouin) Koehne seeds have been evaluated and compared to those of conventional chemical extraction methods (Soxhlet extraction). This oil contains unsaturated fatty acids and polyphenols. Subcritical fluid extraction (SbFE) provided the highest yield—25.79 g oil/100 g dry seeds—of the three methods. Moreover, the fatty acid composition in the oil samples was analysed using gas chromatography–mass spectrometry. This analysis showed that the percentages of monounsaturated (46.61%), and polyunsaturated fatty acids (42.14%), after appl…

FlavonoidPharmaceutical ScienceMass spectrometry01 natural sciencesGas Chromatography-Mass SpectrometryArticleAnalytical Chemistrylcsh:QD241-4410404 agricultural biotechnologylcsh:Organic chemistryResponse surface methodologyDrug DiscoveryPlant OilsProcess optimizationPhysical and Theoretical Chemistry<i>Chaenomelessinensis</i> (Thouin) Koehne seed oil; subcritical fluid extraction; response surface methodology; fatty acid composition; polyphenol contentMicrowavesRosaceaeChaenomelessinensis (Thouin) Koehne seed oil; Fatty acid composition; Polyphenol content; Response surface methodology; Subcritical fluid extraction; Organic Chemistrychemistry.chemical_classificationChromatography010405 organic chemistryPolyphenol contentExtraction (chemistry)Organic ChemistryPilot scalePolyphenols04 agricultural and veterinary sciences040401 food scienceChaenomelessinensis (Thouin) Koehne seed oil0104 chemical scienceschemistryChemistry (miscellaneous)PolyphenolFatty Acids UnsaturatedMolecular MedicineFatty acid compositionFatty acid compositionSubcritical fluid extractionPolyunsaturated fatty acid
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