0000000000200904

AUTHOR

A. Lindner

Axion search with BabyIAXO in view of IAXO

Axions are a natural consequence of the Peccei-Quinn mechanism, the most compelling solution to the strong-CP problem. Similar axion-like particles (ALPs) also appear in a number of possible extensions of the Standard Model, notably in string theories. Both axions and ALPs are very well motivated candidates for Dark Matter, and in addition, they would be copiously produced at the sun's core. A relevant effort during the last decade has been the CAST experiment at CERN, the most sensitive axion helioscope to-date. The International Axion Observatory (IAXO) is a large-scale 4th generation helioscope. As its primary physics goal, IAXO will look for solar axions or ALPs with a signal to backgro…

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Conceptual design of the International Axion Observatory (IAXO)

The International Axion Observatory (IAXO) will be a forth generation axion helioscope. As its primary physics goal, IAXO will look for axions or axion-like particles (ALPs) originating in the Sun via the Primakoff conversion of the solar plasma photons. In terms of signal-to-noise ratio, IAXO will be about 4-5 orders of magnitude more sensitive than CAST, currently the most powerful axion helioscope, reaching sensitivity to axion-photon couplings down to a few $\times 10^{-12}$ GeV$^{-1}$ and thus probing a large fraction of the currently unexplored axion and ALP parameter space. IAXO will also be sensitive to solar axions produced by mechanisms mediated by the axion-electron coupling $g_{…

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First measurement of the |t|-dependence of coherent J/ψ photonuclear production

The first measurement of the dependence on $|t|$, the square of the momentum transferred between the incoming and outgoing target nucleus, of coherent J/ψ photoproduction is presented. The data were measured with the ALICE detector in ultra-peripheral Pb-Pb collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{\rm NN}} = 5.02$ TeV with the J/$\psi$ produced in the central rapidity region $|y| < 0.8$, which corresponds to the small Bjorken-$x$ range $(0.3 − 1.4) \times 10 ^{−3}$. The measured $|t|$-dependence is not described by computations based only on the Pb nuclear form factor, while the photonuclear cross section is better reproduced by models including shadowing according t…

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Dark Sectors and New, Light, Weakly-Coupled Particles

Dark sectors, consisting of new, light, weakly-coupled particles that do not interact with the known strong, weak, or electromagnetic forces, are a particularly compelling possibility for new physics. Nature may contain numerous dark sectors, each with their own beautiful structure, distinct particles, and forces. This review summarizes the physics motivation for dark sectors and the exciting opportunities for experimental exploration. It is the summary of the Intensity Frontier subgroup "New, Light, Weakly-coupled Particles" of the Community Summer Study 2013 (Snowmass). We discuss axions, which solve the strong CP problem and are an excellent dark matter candidate, and their generalizatio…

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IAXO - The International Axion Observatory

The International Axion Observatory (IAXO) is a next generation axion helioscope aiming at a sensitivity to the axion-photon coupling of a few 10^{-12} GeV^{-1}, i.e. 1-1.5 orders of magnitude beyond sensitivities achieved by the currently most sensitive axion helioscope, the CERN Axion Solar Telescope (CAST). Crucial factors in improving the sensitivity for IAXO are the increase of the magnetic field volume together with the extensive use of x-ray focusing optics and low background detectors, innovations already successfully tested at CAST. Electron-coupled axions invoked to explain the white dwarf cooling, relic axions, and a large variety of more generic axion-like particles (ALPs) along…

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Search for a common baryon source in high-multiplicity pp collisions at the LHC

Physics letters / B B811, 135849 (2020). doi:10.1016/j.physletb.2020.135849

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The Next Generation of Axion Helioscopes: The International Axion Observatory (IAXO)

Çetin, Serkant Ali (Dogus Author) -- Conference full title: 13th International Conference on Topics in Astroparticle and Underground Physics, TAUP 2013; Asilomar Conference Grounds Monterey Peninsula; United States; 8 September 2013 through 13 September 2013. The International Axion Observatory (IAXO) is a proposed 4th-generation axion helioscope with the primary physics research goal to search for solar axions via their Primakoff conversion into photons of 1 - 10 keV energies in a strong magnetic field. IAXO will achieve a sensitivity to the axion-photon coupling gaγ down to a few ×10-12 GeV-1 for a wide range of axion masses up to ∼ 0.25 eV. This is an improvement over the currently best …

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Future axion searches with the International Axion Observatory (IAXO)

Çetin, Serkant Ali (Dogus Author) -- Conference full title: 6th Symposium on Large TPCs for Low Energy Rare Event Detection; Paris; France; 17 December 2012 through 19 December 2012. The International Axion Observatory (IAXO) is a new generation axion helioscope aiming at a sensitivity to the axion-photon coupling of gaγ ∼ few × 10-12 GeV-1, i.e. 1-1.5 orders of magnitude beyond the one achieved by CAST, currently the most sensitive axion helioscope. The main elements of IAXO are an increased magnetic field volume together with extensive use of x-ray focusing optics and low background detectors, innovations already successfully tested in CAST. Additional physics cases of IAXO could include …

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Dielectron production in proton-proton and proton-lead collisions at √sNN=5.02TeV

The first measurements of dielectron production at midrapidity (|ηe| &lt; 0.8) in proton–proton and proton–lead collisions at √sNN = 5.02 TeV at the LHC are presented. The dielectron cross section is measured with the ALICE detector as a function of the invariant mass mee and the pair transverse momentum pT, ee in the ranges mee &lt; 3.5 GeV/c2 and pT, ee &lt; 8 GeV/c, in both collision systems. In proton–proton collisions, the charm and beauty cross sections are determined at midrapidity from a fit to the data with two different event generators. This complements the existing dielectron measurements performed at √s = 7 and 13 TeV. The slope of the √s dependence of the three measurements is…

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Intracranial pressure monitoring in patients with acute brain injury in the intensive care unit (SYNAPSE-ICU): an international, prospective observational cohort study

Background: The indications for intracranial pressure (ICP) monitoring in patients with acute brain injury and the effects of ICP on patients’ outcomes are uncertain. The aims of this study were to describe current ICP monitoring practises for patients with acute brain injury at centres around the world and to assess variations in indications for ICP monitoring and interventions, and their association with long-term patient outcomes. Methods: We did a prospective, observational cohort study at 146 intensive care units (ICUs) in 42 countries. We assessed for eligibility all patients aged 18 years or older who were admitted to the ICU with either acute brain injury due to primary haemorrhagic…

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Next Generation Search for Axion and ALP Dark Matter with the International Axion Observatory

International audience; More than 80 years after the postulation of dark matter, its nature remains one of the fundamental questions in cosmology. Axions are currently one of the leading candidates for the hypothetical, non-baryonic dark matter that is expected to account for about 25% of the energy density of the Universe. Especially in the light of the Large Hadron Collider at CERN slowly closing in on Weakly-Interacting Massive Particle (WIMP) searches, axions and axion-like particles (ALPs) provide a viable alternative approach to solving the dark matter problem. The fact that makes them particularly appealing is that they were initially introduced to solve a long-standing problem in qu…

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Physics beyond colliders at CERN: beyond the Standard Model working group report

The Physics Beyond Colliders initiative is an exploratory study aimed at exploiting the full scientific potential of the CERN's accelerator complex and scientific infrastructures through projects complementary to the LHC and other possible future colliders. These projects will target fundamental physics questions in modern particle physics. This document presents the status of the proposals presented in the framework of the Beyond Standard Model physics working group, and explore their physics reach and the impact that CERN could have in the next 10–20 years on the international landscape.

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Klinische Pharmakologie I

Rifampicin (RMP) induziert nach mehrtagiger Gabe die mischfunktionellen Oxygenasen in der Leber, so das auch sein eigener Metabolismus beschleunigt wird (Eigeninduktion, Acocella 1978a). Wie wir beobachteten, nahmen die RMP-Plasmaspiegel unter oraler Dauertherapie starker ab als bei intravenoser Applikation (Musch et al. 1982; Loos et al. 1983). Klinisch zeigten 30 initial mit RMP intravenos behandelte Patienten mit offener Lungentuberkulose eine schnellere Sputumnegativierung und Rontgenbefundbesserung im Vergleich zu 48 oral therapierten Patienten (Kombinationstherapie: RMP-Isoniazid-Ethambutol). So war z. B. die Sputumkulturkonversion nach dem 1. Behandlungsmonat bei intravenoser RMP-Gab…

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Measurements of mixed harmonic cumulants in Pb–Pb collisions at sNN=5.02 TeV

Correlations between moments of different flow coefficients are measured in Pb–Pb collisions at sNN=5.02 TeV recorded with the ALICE detector. These new measurements are based on multiparticle mixed harmonic cumulants calculated using charged particles in the pseudorapidity region |η|&lt;0.8 with the transverse momentum range 0.2&lt;pT&lt;5.0 GeV/c. The centrality dependence of correlations between two flow coefficients as well as the correlations between three flow coefficients, both in terms of their second moments, are shown. In addition, a collection of mixed harmonic cumulants involving higher moments of v2 and v3 is measured for the first time, where the characteristic signature of ne…

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