A novel epitope of N-CAM defines precursors of human adherent NK cells
AbstractActivated, adherent natural killer (A-NK) cells represent a distinct subpopulation of interleukin (IL)-2-stimulated NK cells, which are selectively endowed with the increased expression of integrins and ability to adhere to solid surfaces, migrate into, infiltrate, and destroy cancerous tissues. The present study defines the phenotype and functions of precursors of A-NK (pre-A-NK) cells in humans. Peripheral blood pre-A-NK cells, in contrast to the rest of NK cells, express a novel epitope of CD56 neuronal cell adhesion molecule, termed ANK-1, and increased cell-surface levels of integrins. Pre-A-NK cells also express low levels of CD56 and CD161, and some express CD162 receptor, do…
An original method to compute epipoles using variable homography: application to measure emergent fibers on textile fabrics
International audience; Fabric's smoothness is a key factor to determine the quality of finished textile products and has great influence on the functionality of industrial textiles and high-end textile products. With popularization of the 'zero defect' industrial concept, identifying and measuring defective material in the early stage of production is of great interest for the industry. In the current market, many systems are able to achieve automatic monitoring and control of fabric, paper, and nonwoven material during the entire production process, however online measurement of hairiness is still an open topic and highly desirable for industrial applications1. In this paper we propose a …
A New Method to Measure 3D Textile Defects by Using Dual-lens Camera
International audience; Industrial textile fabric with functionalization always has a high standard requirement. Take polytetrafluoroethylene (PTFE) conveyor belt as an example, the base fabrics must be of first-rate quality, with no weaving faults or broken fibers on coated surface [1]. In a previous work, we have proposed an original method to measure the height of the fiber based on variable homography. This measurement is based on a single camera acquiring two successive frames. This scheme is working well, but measurement depends on conveyor speed used for scrolling fabric. In this paper, we propose an improvement by using a new acquisition device based on two mini-lenses assembled as …
Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types
BACKGROUND: Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide polymorphisms (SNPs) for cancer at 13 anatomical sites.METHODS: Between 2007 and 2014, the US National Cancer Institute has generated data from genome-wide association studies (GWAS) for 49 492 cancer case patients and 34 131 control patients. We apply novel mixed model methodology (GCTA) to this GWAS data to estimate the heritability of individual cancers, as well as the proportion of heritability attributable to cigarette smoking in smoking-related cance…