0000000000201275

AUTHOR

F. Galeotti

showing 2 related works from this author

Brainstem reflex circuits revisited

2004

Our current understanding of brainstem reflex physiology comes chiefly from the classic anatomical-functional correlation studies that traced the central circuits underlying brainstem reflexes and establishing reflex abnormalities as markers for specific areas of lesion. These studies nevertheless had the disadvantage of deriving from post-mortem findings in only a few patients. We developed a voxel-based model of the human brainstem designed to import and normalize MRIs, select groups of patients with or without a given dysfunction, compare their MRIs statistically, and construct three-plane maps showing the statistical probability of lesion. Using this method, we studied 180 patients with…

Adult; Aged; 80 and over; Blinking; Brain Stem Infarctions; diagnosis/physiopathology; Brain Stem; physiopathology; Electromyography; Female; Humans; Jaw; Magnetic Resonance Imaging; Male; Masseter Muscle; Middle Aged; Reflex; AbnormalAdultMalemedicine.medical_specialtyBrain Stem InfarctionsClinical neurophysiologyReflex80 and overmedicineHumansCorneal reflexAgedAged 80 and overBlinkingReflex AbnormalElectromyographyMasseter MuscleDental occlusionAnatomyMiddle AgedMagnetic Resonance Imagingdiagnosis/physiopathologyPonsJawCiliospinal reflexAbnormalReflexFemaleNeurology (clinical)BrainstemphysiopathologyPsychologyJaw jerk reflexBrain StemBrain
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Topodiagnostic implications of hemiataxia: An MRI-based brainstem mapping analysis

2007

The topodiagnostic implications of hemiataxia following lesions of the human brainstem are only incompletely understood. We performed a voxel-based statistical analysis of lesions documented on standardised MRI in 49 prospectively recruited patients with acute hemiataxia due to isolated unilateral brainstem infarction. For statistical analysis individual MRI lesions were normalised and imported in a three-dimensional voxel-based anatomical model of the human brainstem. Statistical analysis revealed hemiataxia to be associated with lesions of three distinct brainstem areas. The strongest correlation referred to ipsilateral rostral and dorsolateral medullary infarcts affecting the inferior ce…

AdultMalePathologymedicine.medical_specialtyAtaxiaInferior cerebellar peduncleCognitive NeuroscienceFunctional LateralityBrain IschemiaLesionCerebellumPonsImage Processing Computer-AssistedmedicineHumansProspective StudiesmriAgedAged 80 and overMedulla OblongataPontine BaseSpinocerebellar tractbusiness.industryataxiaDorsal spinocerebellar tractCerebral Infarctionataxia; brain mapping; brain stem; mriAnatomyMiddle AgedMagnetic Resonance ImagingPonsParesismedicine.anatomical_structureNeurologySpinocerebellar Tractsbrain mappingFemaleBrainstemmedicine.symptombrain stembusinessNeuroImage
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