0000000000202273

AUTHOR

Paolisso G.

showing 4 related works from this author

The extreme longevity: the state of the art in Italy

2008

GerontologyMaleAgingmedia_common.quotation_subjectHealth StatusLongevityBiochemistryEndocrinologyState (polity)Development economicsGeneticsDiabetes MellitusMedicineHumansMolecular Biologymedia_commonAged 80 and overbusiness.industryCell BiologyGene Expression RegulationItalyCardiovascular DiseasesImmune SystemExtreme longevity trackingFemalebusiness
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The cortisol burden in elderly subjects with metabolic syndrome and its association with low-grade inflammation

2019

Background: Elderly people are exposed to an increased load of stressful events and neuro-hormonal stimulation is a key finding in metabolic syndrome and its related disorders. Aims: To determine the role of cortisol in elderly subjects, with or without metabolic syndrome (MetS), by means of a national multicentre observational study, AGICO (AGIng and Cortisol). Methods: From 2012 to 2017, the AGICO study enrolled n.339 subjects (aged > 65), after obtaining their informed consent. The investigators assessed a cardio-metabolic panel (including electrocardiogram, carotid ultrasonography and echocardiography), the presence of MetS (on Adult Treatment Panel III criteria), a neurological exam…

MaleAgingmedicine.medical_specialtySettore MED/09 - Medicina InternaHydrocortisoneUrinary systemNeurological examinationUrineGastroenterologyCortisolaging; cortisol; Inflammation; metabolic syndrome; aged; aged; 80 and over; echocardiography; female; humans; hydrocortisone; inflammation; male; metabolic syndromeExcretionAging; Cortisol; Inflammation; Metabolic syndrome; Aged; Aged 80 and over; Echocardiography; Female; Humans; Hydrocortisone; Inflammation; Male; Metabolic Syndrome03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicine80 and overmedicineHumans030212 general & internal medicineAgedAged 80 and overInflammationCreatininemedicine.diagnostic_testbusiness.industryCarotid ultrasonographymedicine.diseaseMetabolic syndromechemistryEchocardiographyFemaleGeriatrics and GerontologyMetabolic syndromebusiness030217 neurology & neurosurgeryHormone
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The multifaceted spectrum of liver cirrhosis in older hospitalised patients: Analysis of the REPOSI registry

2021

Abstract Background Knowledge on the main clinical and prognostic characteristics of older multimorbid subjects with liver cirrhosis (LC) admitted to acute medical wards is scarce. Objectives To estimate the prevalence of LC among older patients admitted to acute medical wards and to assess the main clinical characteristics of LC along with its association with major clinical outcomes and to explore the possibility that well-distinguished phenotypic profiles of LC have classificatory and prognostic properties. Methods A cohort of 6,193 older subjects hospitalised between 2010 and 2018 and included in the REPOSI registry was analysed. Results LC was diagnosed in 315 patients (5%). LC was ass…

Patient Discharge.RegistrieAgingmedicine.medical_specialtyCirrhosisphenotypeliver cirrhosisAftercareOlder populationNOolder people03 medical and health sciencesSocial support0302 clinical medicinePhenotypic analysisOlder patientsInternal medicinemedicineHumansRegistries030212 general & internal medicineLS4_4Hospital MortalityAgedbusiness.industryhospitalisationliver cirrhosiHazard ratioConfoundingphenotypesGeneral Medicinemedicine.diseasedisability; hospitalisation; liver cirrhosis; mortality; older people; phenotypes; Aged; Hospital Mortality; Hospitalization; Humans; Liver Cirrhosis; Registries; Aftercare; Patient DischargemortalityPatient DischargeHospitalizationdisabilityCohortdisability hospitalisation liver cirrhosis mortality older people phenotypes030211 gastroenterology & hepatologyGeriatrics and Gerontologybusinessdisability; hospitalisation; liver cirrhosis; mortality; older people; phenotypesHuman
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Underdiagnosis and undertreatment of osteoporotic patients admitted in internal medicine wards in Italy between 2010 and 2016 (the REPOSI Register)

2021

Purpose: To evaluate clinical features, treatments, and outcomes of osteoporotic patients admitted to internal medicine and geriatric wards compared with non-osteoporotic patients (REPOSI registry). Methods: We studied 4714 patients hospitalized between 2010 and 2016. We reported age, sex, educational level, living status, comorbidities and drugs taken, Cumulative Illness Rating Scale (CIRS), Barthel Index, Short-Blessed Test, 4-item Geriatric Depression Scale, serum hemoglobin, creatinine, and clinical outcomes. Osteoporosis was defined based on the diagnoses recorded at admission, according to the following ICD9: 733, 805-813, 820-823. Results: Twelve percent of the patients had a preadmi…

medicine.medical_specialtyEndocrinology Diabetes and Metabolismmedicine.medical_treatmentOsteoporosis030209 endocrinology & metabolismNO03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEndocrinologyRating scaleInternal medicineDiabetes mellitusVitamin D and neurologyInternal MedicineMedicineeracturesHumansBisphosphonateMedical diagnosisbisphosphonates; eractures; osteoporosis; vitamin DVitamin DAgedCreatinineRehabilitationLS7_9Bisphosphonates; Fractures; Osteoporosis; Vitamin D.business.industryOsteoporosiBisphosphonatesmedicine.diseaseHospitalizationFracturechemistryItaly030220 oncology & carcinogenesisOsteoporosisGeriatric Depression ScaleVitamin D.businessBisphosphonates; Fractures; Osteoporosis; Vitamin D; Aged; Hospitalization; Humans; Internal Medicine; Italy; Vitamin D; OsteoporosisBisphosphonates; Fractures; Osteoporosis; Vitamin DFractures
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