0000000000205902

AUTHOR

Nikolaos Donos

showing 3 related works from this author

Lipid subclasses profiles and oxidative stress in aggressive periodontitis before and after treatment

2015

Background and Objective: Associations between dyslipidaemia, oxidative stress and periodontitis have emerged in recent years. However, there is a lack of studies investigating these associations in aggressive periodontitis (AgP) cases. The aim of this study was to investigate the lipid and oxidative stress profiles in patients with AgP, and to relate them to clinical variables and interleukin (IL)-6 genetic variants. Material and Methods: Twelve non-smoking Caucasian patients with AgP selected based on their IL6 haplotypes underwent periodontal non-surgical and surgical treatment. Peripheral blood samples taken at baseline and at six different time-points after treatment were processed to …

AdultMalemedicine.medical_specialtyAdolescentEuropean Continental Ancestry GroupLongitudinal Studiemedicine.disease_causeWhite Peoplechemistry.chemical_compoundYoung AdultGeneticInternal medicinemedicineHaplotypeAggressive periodontitisHumansLongitudinal StudiesPeriodontitismedicine.diagnostic_testCholesterolbusiness.industryInterleukin-6PeriodontitiOxidative Stress.BiomarkerLipidmedicine.diseaseLipidsAggressive PeriodontitiOxidative StressEndocrinologyTreatment OutcomechemistryAggressive PeriodontitisHaplotypesPeriodonticsOxidative strelipids (amino acids peptides and proteins)FemaleMetabolic syndromebusinessLipid profileDyslipidemiaOxidative stressBiomarkersLipoproteinHuman
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Healing of intrabony defects following treatment with a bovine-derived xenograft and collagen membrane

2003

Objectif: L'objectif de cette etude etait de comparer cliniquement le traitement de lesions intra-osseuses profondes avec xenogreffe d'origine bovine (BDX) associe a une membrane collagene bioresorbable pour acceder a la chirurgie a lambeau. Methode: Vingt-huit malades souffrant de parodontite chronique, chacun montrant une lesion intra-osseuse ont ete traites au hasard au BDX+membrane collagene (essai) ou avec chirurgie a lambeau (controle). Les mesures des tissus mous ont ete prises au depart et 1 an apres la therapie. Resultats: Aucune difference dans aucun des parametres etudies n'a ete observee au depart entre les deux groupes. La cicatrisation a ete sans incident pour tous les malades…

MaleMatched Pair Analysismedicine.medical_specialtyMatched-Pair AnalysisTransplantation HeterologousAlveolar Bone LossBone MatrixBone matrixSurgical FlapsClinical studyAbsorbable ImplantsPeriodontal Attachment LossmedicineAnimalsHumansPeriodontal PocketPeriodontitisGynecologyMineralsWound Healingbusiness.industryCollagen membraneFollow up studiesMembranes ArtificialSurgeryChronic diseaseBone SubstitutesChronic DiseasePeriodonticsCattleFemaleCollagenbusinessFollow-Up StudiesJournal of Clinical Periodontology
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Immunohistochemical evaluation of matrix molecules associated with wound healing following treatment with an enamel matrix protein derivative in huma…

2003

Application of enamel matrix protein derivative (EMD) onto a debrided and conditioned root surface has been shown to promote periodontal regeneration in animals and humans. However, until now there is virtually no information from humans describing the expression of different matrix molecules in the newly formed periodontal tissues following treatment with EMD. This study investigated immunohistochemically in humans the expression of matrix molecules associated with periodontal tissues reformed after treatment with EMD. Eight patients with intrabony defects were treated with EMD. Six months after surgery teeth together with some of their surrounding soft and hard tissues were removed, fixed…

PeriodontiumPathologymedicine.medical_specialtyBone RegenerationPeriodontal LigamentSialoglycoproteinsAlveolar Bone LossMedizinMatrix (biology)Collagen Type I03 medical and health sciencesCollagen Type III0302 clinical medicineDental Enamel ProteinsAlveolar ProcessmedicineHumansRegenerationPeriodontal fiberCementumBone regenerationGeneral DentistryDental alveolus030304 developmental biologyDental CementumExtracellular Matrix ProteinsWound Healing0303 health sciencesChemistry030206 dentistryAnatomyPhosphoproteinsImmunohistochemistryCollagen Type IIImedicine.anatomical_structureConnective TissueGuided Tissue Regeneration PeriodontalOsteopontinBone RemodelingDental cementumWound healingClinical Oral Investigations
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