0000000000208653

AUTHOR

Massimiliano Raponi

showing 3 related works from this author

School in Italy: a safe place for children and adolescents

2021

AbstractBackgroundDuring the first SARS-CoV-2 pandemic phase, the sudden closure of schools was one of the main measures to minimize the spread of the virus. In the second phase, several safety procedures were implemented to avoid school closure.To evaluate if the school is a safe place, students and staff of two school complexes of Rome were monitored to evaluate the efficacy of prevention measures inside the school buildings.MethodsOral secretions specimens were collected from 1262 subjects for a total of 3431 samples, collected over a 3 months period.Detection of Coronavirus SARS-CoV-2 was performed by real-time PCR. Target genes were represented by E gene, RdRP/S gene and N gene.Results…

MaleSchoolPrevention measuresmedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)AdolescentPrevention measureSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViraleducationSample (statistics)030226 pharmacology & pharmacy03 medical and health sciences0302 clinical medicineCOVID-19 TestingPandemicDisease Transmission InfectiousMedicineHumansOral secretions030212 general & internal medicineChildPandemicsSchool Health ServicesCOVIDInfection Controlbusiness.industryMaternal and child healthSARS-CoV-2School.Researchlcsh:RJ1-570COVID-19lcsh:PediatricsGeneral MedicineSettore MED/38ItalyFamily medicineFemalePrevention controlbusinessItalian Journal of Pediatrics
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Different Innate and Adaptive Immune Responses to SARS-CoV-2 Infection of Asymptomatic, Mild, and Severe Cases

2020

Abstract Background SARS-CoV-2 is a novel coronavirus, not encountered before by humans. The wide spectrum of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to SARS-CoV-2 play a crucial role in determining the clinical course after first infection. Immunological studies have focussed on patients with moderate to severe disease, demonstrating excessive inflammation in tissues and organ damage. We have studied the individual response to SARS-CoV-2 of asympromatic, mild and severe COVID-19 patients in order to investigate the role of innnate and adaptive immunity in determining the clinical course after first infection. Methods To understand the basis of th…

0301 basic medicineAdultMalelcsh:Immunologic diseases. AllergyImmunologyInflammationDiseaseAdaptive Immunitymedicine.disease_causeAntibodies ViralAsymptomaticSeverity of Illness IndexSerology03 medical and health sciences0302 clinical medicineImmune systeminnate and adaptiveimmune responsemedicineHumansImmunology and AllergyantibodiesNK cellOriginal ResearchCoronavirusB cellsbiologybusiness.industrySARS-CoV-2MonocyteSettore BIO/12COVID-19antibodies; B cells; COVID-19; innate and adaptiveimmune response; monocytes; NK cell; SARS-CoV-2Acquired immune systemImmunity InnateImmunoglobulin AKiller Cells Natural030104 developmental biologymedicine.anatomical_structureImmunoglobulin MSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA030220 oncology & carcinogenesisImmunologybiology.proteinFemalemedicine.symptomAntibodybusinesslcsh:RC581-607monocytes
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Additional file 1 of The pandemic within the pandemic: the surge of neuropsychological disorders in Italian children during the COVID-19 era

2022

Additional file1: Table S1. Regional centers enrolled in the study, list of hospitals and departments involved in the study.

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