0000000000210323

AUTHOR

Susann Wichmann

showing 2 related works from this author

Stress-induced pro- and anti-inflammatory cytokine concentrations in panic disorder patients

2018

Abstract Background An attenuated responsivity of the hypothalamus–hypophysis-adrenal (HPA) axis upon challenge and an increased risk for cardiac events are relatively consistent findings in panic disorder (PD) patients. Due to cytokine-HPA interactions, an altered HPA-axis responsivity may be accompanied by altered cytokine concentrations. Immunological reactions under stress might be considered the missing link for explaining an increased cardiac risk. This study analyzed stress-induced cytokine levels in PD patients. Methods A total of n = 32 PD patients and n = 32 healthy control individuals performed the Trier Social Test (TSST). Blood sample collection accompanied the TSST for the col…

AdultMaleHypothalamo-Hypophyseal Systemmedicine.medical_specialtyHydrocortisonemedicine.drug_classEndocrinology Diabetes and Metabolismmedicine.medical_treatmentPituitary-Adrenal SystemDiseaseAnti-inflammatory03 medical and health sciences0302 clinical medicineEndocrinologyInternal medicinemedicineHumansSalivaBiological PsychiatryPsychiatric Status Rating ScalesInterleukin-6Tumor Necrosis Factor-alphaEndocrine and Autonomic Systemsbusiness.industryPanic disorderPanicRepeated measures designMiddle Agedmedicine.diseaseInterleukin-10030227 psychiatryPsychiatry and Mental healthDistressEndocrinologyCytokineCase-Control StudiesCytokinesPanic DisorderFemaleSample collectionmedicine.symptombusinessStress Psychological030217 neurology & neurosurgeryPsychoneuroendocrinology
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Hair cortisol predicts avoidance behavior and depressiveness after first-time and single-event trauma exposure in motor vehicle crash victims

2020

The role of cortisol as a premorbid vulnerability factor for trauma sequelae remains unclear. Furthermore, the onset of long-term endocrine changes in response to first-time trauma as a function of later psychopathology is not clarified yet. Thus the predictive value of pre- and post-traumatic hair cortisol concentrations (HCCs) for psychological trauma sequelae was investigated in response to motor vehicle crash (MVC). A total of

medicine.medical_specialtyHydrocortisonePhysiologyEvent (relativity)Vulnerability factorStress Disorders Post-Traumatic03 medical and health sciencesBehavioral Neuroscience0302 clinical medicinePhysical medicine and rehabilitationAvoidance LearningHumansMedicineProspective StudiesEndocrine and Autonomic Systemsbusiness.industry030227 psychiatryMotor VehiclesPsychiatry and Mental healthNeuropsychology and Physiological PsychologyFemalesense organsbusinessStress Psychological030217 neurology & neurosurgeryMotor vehicle crashStress
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