0000000000211416

AUTHOR

Harith Akram

showing 2 related works from this author

Normative vs. patient-specific brain connectivity in Deep Brain Stimulation

2020

AbstractBrain connectivity profiles seeding from deep brain stimulation (DBS) electrodes have emerged as informative tools to estimate outcome variability across DBS patients. Given the limitations of acquiring and processing patient-specific diffusion-weighted imaging data, most studies have employed normative atlases of the human connectome. To date, it remains unclear whether patient-specific connectivity information would strengthen the accuracy of such analyses. Here, we compared similarities and differences between patient-specific, disease-matched and normative structural connectivity data and retrospective estimation of clinical improvement that they may generate.Data from 33 patien…

0303 health sciencesmedicine.medical_specialtyMotor areaDeep brain stimulationSupplementary motor areabusiness.industrymedicine.medical_treatmentHuman ConnectomePatient specific03 medical and health sciences0302 clinical medicinemedicine.anatomical_structurePhysical medicine and rehabilitationmedicineConnectomeNormativePrimary motor cortexbusiness030217 neurology & neurosurgery030304 developmental biology
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Normative vs. patient-specific brain connectivity in deep brain stimulation

2020

Abstract Brain connectivity profiles seeding from deep brain stimulation (DBS) electrodes have emerged as informative tools to estimate outcome variability across DBS patients. Given the limitations of acquiring and processing patient-specific diffusion-weighted imaging data, a number of studies have employed normative atlases of the human connectome. To date, it remains unclear whether patient-specific connectivity information would strengthen the accuracy of such analyses. Here, we compared similarities and differences between patient-specific, disease-matched and normative structural connectivity data and their ability to predict clinical improvement. Data from 33 patients suffering from…

AdultMalemedicine.medical_specialtyDeep brain stimulationParkinson's diseaseCognitive Neurosciencemedicine.medical_treatmentSubthalamic nucleusImaging data050105 experimental psychologylcsh:RC321-57103 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationConnectomeDeep brain stimulationmedicineHumans0501 psychology and cognitive scienceslcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBrain MappingModalitiesbusiness.industry05 social sciencesBrainHuman ConnectomeMiddle AgedPatient specificMagnetic Resonance ImagingHuman connectomeNeurologyConnectomeNormativeFemalebusinessTractography030217 neurology & neurosurgeryTractographyNeuroImage
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