0000000000212521
AUTHOR
S Omboni
Vascular health assessment of the hypertensive patients (VASOTENS) Registry: rationale, design and methods of an international registry for ambulatory blood pressure and arterial stiffness telemonitoring
Ambulatory (A) blood pressure (BP), central BP and pulse wave velocity (PWV) are parameters recommended by hypertension guidelines for estimating BP control and vascular impairment. Recent advances in technology made available devices allowing combined non-invasive estimation of these parameters over the 24-h during ABP monitoring (ABPM). However, at present, there is limited evidence on the usefulness of such an approach for routine hypertension managementWe recently launched an investigator-initiated, international, multicenter, observational, prospective study with the following objectives: • The evaluation of non-invasive ambulatory blood pressure and arterial stiffness estimates (throu…
Frovatriptan versus almotriptan for acute treatment of menstrual migraine: analysis of a double-blind, randomized, cross-over, multicenter, Italian, comparative study
The objective of the study was to compare the efficacy and safety of frovatriptan and almotriptan in women with menstrually related migraine (IHS Classification of Headache disorders) enrolled in a multicenter, randomized, double-blind, cross-over study. Patients received frovatriptan 2.5 mg or almotriptan 12.5 mg in a randomized sequence: after treating 3 episodes of migraine in no more than 3 months with the first treatment, the patient was switched to the other treatment. 67 of the 96 female patients of the intention-to-treat population of the main study had regular menstrual cycles and were thus included in this subgroup analysis. 77 migraine attacks classified as related to menses were…