0000000000212742
AUTHOR
Gordon Proctor
Salivary protein markers of type 2 diabetes mellitus in elderly subjects and links with dietary habits
National audience
Optimization of saliva sample preparation and analysis for identification of protein biomarkers
National audience
Mediation analysis to understand the role of overweight on the relationship between Mediterranean diet and risk of type 2 diabetes mellitus: evidence from 21 612 UKBiobank participants
Adhérence au régime méditerranéen, indice de masse corporelle et risque de diabète de type 2 : résultats de l’étude UK Biobank
Discipline Epidemiologie. Introduction et but de l’etude Au cours des dernieres decennies, l’incidence du diabete de type II (DT2) a augmente de maniere significative a travers le monde, entrainant une augmentation de la morbidite et de la mortalite associees. En termes de prevention, les preuves s’accumulent quant a l’association entre l’adherence a un regime de type Mediterraneen et un moindre risque de DT2. Dans cette etude, nous nous sommes interesses a l’effet potentiellement mediateur de l’indice de masse corporelle (IMC) en tant que mecanisme sous-jacent a cette relation. Materiel et methodes Les participants de la UK Biobank ayant des donnees cliniques sur le statut diabetique et ay…
Adhérence au régime Méditerranéen, indice de masse corporelle et risque de diabète de type 2 : Résultats de l'étude UKBiobank
The role of overweight in the association between the Mediterranean diet and the risk of type 2 diabetes mellitus: a mediation analysis among 21 585 UK biobank participants
Abstract Background There is growing evidence that the Mediterranean (Medi) diet may lower the risk of type 2 diabetes mellitus (T2DM). Whether this association is due to the Medi diet by itself or is mediated by a diet-associated lower rate of overweight is uncertain. Our aim was to disentangle these relationships among UK adults. Methods Based on 21 585 participants from the UK Biobank cohort, the adherence to the Medi diet (high fruits, vegetables, legumes, cereals, fish, olive oil; low meat, dairy products; and intermediate alcohol intakes) was assessed (range 0–18). Data on diabetes were self-reported, and overweight was defined as a body mass index (BMI) ≥ 25 kg/m². A mediation analys…