0000000000213326
AUTHOR
Nadine Metz
Substrate-Independent Stable and Adherent Reactive Surface Coatings and their Conversion with Amines
To create stable, adherent and reactive surface coatings, a hybrid polymer composed of poly(methylsilsesquioxane) (PMSSQ) and poly(pentafluorophenyl acrylate) PFPA with a M n of 32000 g/mol was prepared by a RAFT polymerization procedure. These hybrid polymer has been used for coating experiments. The PFPA part enabled a variable functionalization of the coating afterwards. The stability on various substrates (e.g. glass, PMMA, steel) was tested in an ISO tape test. These reactive surface coatings were modified using different amines, such as amino-terminated PEG, dodecyl amine and N-isopropyl amine. The conversion was analyzed by FT-IR and contact angle measurements.
Cyclodextrins in Polymer Synthesis: Free-Radical Polymerization of Methylated β-Cyclodextrin Complexes of Methyl Methacrylate and Styrene Controlled by N-Acetyl-l-cysteine as a Chain-Transfer Agent in Aqueous Medium
Multifunctional polymer-derivatized γ-Fe2O3 nanocrystals as a methodology for the biomagnetic separation of recombinant His-tagged proteins
Abstract Multifunctional polymer-derivatized superparamagnetic iron oxide (γ-Fe2O3) nanoparticles were prepared for biomagnetic separation of histidine-tagged recombinant proteins building up a faster and efficient method for protein separation by making use of their intrinsic magnetic properties. Using polymer bound γ-Fe2O3 nanocrystals, a 6× histidine-tagged recombinant protein (silicatein) with a molecular weight of 24 kDa has been isolated and purified. The supermagnetic iron oxide nanocrystals were characterized by transmission electron microscopy (TEM), high-resolution TEM (HRTEM), SQUID and Mossbauer and the polymer functionalization of the γ-Fe2O3 nanocrystals was monitored by UV–vi…
Synthesis and immobilization of molecular switches onto titaniumdioxide nanowires
Abstract The precursor [Fe III (L)Cl (L = N , N ′-bis(2′-hydroxy-3′-methyl-benzyliden)-1,7-diamino-4-azaheptane) is combined with [Mo(CN) 8 ] 4− yields a star shaped nona-nuclear cluster, [Mo IV {(CN)Fe III (L)} 8 ]Cl 4 . This Fe 8 Mo molecule is a high-spin system at room temperature. On cooling to 20 K some of the iron(III) centres in the molybdenum(IV)-star switch to the low-spin state as proven by Mossbauer spectroscopy. This molecule was deposited on TiO 2 nanowires by electrostatic interactions between the cluster cations and the surface functionalized titanium oxide nanowire. The synthesis and surface binding of the multistable molecular switch was demonstrated using IR and UV–Vis s…
Functional Polymer-Opals from Core-Shell Colloids
Colloidal photonic crystals were prepared from monodisperse core-shell particles. The shell is hereby formed from a functional monomer, such as glycidylmethacrylate or different reactive ester monomers, which can perform chemical reactions and the core from a standard monomer, which yields highly monodisperse colloids. It was possible to crystallize the core-shell particles into artificial opals with excellent optical properties. Reactions on the functional surface of the colloids were carried out, which lead to a dramatic rise in the mechanical stability or to a functionalization of His-tagged silicatein, which acts as nanoreactor to synthesize and immobilize gold nanoparticles from auric …
Influence of Binding-Site Density in Wet Bioadhesion
dsRNA-functionalized multifunctional gamma-Fe2O3 nanocrystals: a tool for targeting cell surface receptors.
Enzyme-Mediated Deposition of a TiO2Coating onto Biofunctionalized WS2 Chalcogenide Nanotubes
A chemically specific and facile method for the biofunctionalization of WS2 nanotubes (NT-WS2) is reported. The covalent modification strategy is based on the affinity of the nitrilotriacetic acid (NTA) side chain, which serves as a ligand for the surface binding to NT-WS2 and simultaneously as an anchor group for the binding of His-tagged proteins to the polymer backbone. The polymer functionalized WS2 nanotubes can be solubilized either in water or organic solvents; they are stable for at least one week. The probes were characterized by FT-IR and UV-vis spectroscopy. The immobilization of silicatein, a hydrolytic protein encountered in marine sponges, was visualized by scanning force micr…
dsRNA-funktionalisierte γ-Fe2O3-Nanokristalle: ein Instrument zur gezielten Adressierung von Rezeptoren an der Zelloberfläche
Synthese von komplexen Polymerarchitekturen durch die kontrollierte Polymerisation von Reaktivester-Monomeren
Controlled synthesis of poly(acetone oxime acrylate) as a new reactive polymer: Stimuli-responsive reactive copolymers
Abstract Acetone oxime acrylate has been synthesized as a new active ester monomer. Free radical polymerization yielded a reactive polymer soluble in various organic solvents, such as chloroform, dioxane, DMSO, acetone, methanol, dichloromethane, DMF, and ethanol. Controlled radical polymerization of acetone oxime acrylate was successfully conducted using the RAFT, NMP and Iniferter method. Partly polymer analogous reaction with N-isopropylamine resulted in the reactive copolymer poly(N-isopropylacrylamide-co-acetone oxime acrylate), which featured a lower critical solution temperature (LCST) of 61 °C in water. Further, the reactivity of the copolymer was exemplary proven by complete reacti…