0000000000214257

AUTHOR

Galina Velikova

showing 5 related works from this author

PCN378 - MINIMALLY IMPORTANT DIFFERENCES FOR INTERPRETING EORTC QLQ-C30 SCORES IN MELANOMA, BREAST CANCER AND HEAD AND NECK CANCER PATIENTS ON BEHALF…

2018

Oncologymedicine.medical_specialtybusiness.industryHealth PolicyEortc qlq c30MelanomaHead and neck cancerPublic Health Environmental and Occupational Healthmedicine.diseaseBreast cancerQuality of lifeInternal medicinemedicineHead and neckbusinessValue in Health
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The EORTC computer-adaptive tests measuring physical functioning and fatigue exhibited high levels of measurement precision and efficiency

2013

Objectives: The European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Group is developing a computer-adaptive test (CAT) version of the EORTC Quality of Life Questionnaire (QLQ-C30). We evaluated the measurement properties of the CAT versions of physical functioning (PF) and fatigue (FA) and compared these with the corresponding QLQ-C30 scales. Study Design and Setting: Based on international samples of more than 1,000 cancer patients, we simulated CAT administration of varying numbers of items and compared the resulting scores with those based on all items in the respective item pools. Furthermore, the relative validity (RV) of CATs was compared with that of th…

MESH: FatigueMaleEpidemiologyMESH: Aged 80 and over0302 clinical medicinePhysical functioningQuality of lifeNeoplasmsSurveys and QuestionnairesActivities of Daily LivingStatisticsMESH: NeoplasmsDiagnosis Computer-Assisted030212 general & internal medicineFatigueReliability (statistics)MathematicsMESH: AgedAged 80 and overMESH: Middle AgedMiddle Agedhumanities3. Good healthMESH: Reproducibility of ResultsLevel of measurementMESH: Young AdultData Interpretation Statistical030220 oncology & carcinogenesis/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleAdultmedicine.medical_specialtyAdolescentMean squared errorSensitivity and SpecificityYoung Adult03 medical and health sciencesSDG 3 - Good Health and Well-beingotorhinolaryngologic diseasesmedicineHumansMESH: Surveys and QuestionnairesAgedMESH: AdolescentMESH: HumansMESH: Activities of Daily LivingMESH: Diagnosis Computer-AssistedMESH: Quality of LifeReproducibility of ResultsMESH: Adultsocial sciencesMESH: MaleMESH: Sensitivity and SpecificitySample size determinationQuality of LifePhysical therapy[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieComputerized adaptive testingMESH: Data Interpretation StatisticalMESH: FemaleRelative validity
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Design of a randomized controlled trial of physical training and cancer ( Phys-Can) the impact of exercise intensity on cancer related fatigue, quali…

2017

Background: Cancer-related fatigue is a common problem in persons with cancer, influencing health-related quality of life and causing a considerable challenge to society. Current evidence supports the beneficial effects of physical exercise in reducing fatigue, but the results across studies are not consistent, especially in terms of exercise intensity. It is also unclear whether use of behaviour change techniques can further increase exercise adherence and maintain physical activity behaviour. This study will investigate whether exercise intensity affects fatigue and health related quality of life in persons undergoing adjuvant cancer treatment. In addition, to examine effects of exercise …

MaleQuality of lifeCancer Researchmedicine.medical_specialtyActivities of daily livingBreast NeoplasmsPhysical exerciselcsh:RC254-282law.inventionStudy Protocol03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationQuality of life (healthcare)Cancer SurvivorsRandomized controlled trialEndurance traininglawBehaviour change techniquesGeneticsmedicineHumans030212 general & internal medicineCancer-related fatigueFatigueCancerCancer och onkologibusiness.industryCancer; Physical exercise; Behaviour change techniques; Fatigue; Biological mechanism; Quality of life; Randomized controlled trialProstatic NeoplasmsPhysical exerciseBiological mechanismlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensExercise TherapyMoodOncologyPhysical FitnessRandomized controlled trial030220 oncology & carcinogenesisCancer and OncologyExercise intensityPhysical therapyFemalemedicine.symptomColorectal Neoplasmsbusiness
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Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovaria…

2013

Summary Background In the Gynecologic Cancer Intergroup International Collaboration on Ovarian Neoplasms 7 (ICON7) trial, bevacizumab improved progression-free survival in patients with ovarian cancer when used in combination with first-line chemotherapy and as a single-drug continuation treatment for 18 cycles. In a preliminary analysis of a high-risk subset of patients, there was also an improvement in overall survival. This study aims to describe the health-related quality-of-life (QoL) outcomes from ICON7. Methods ICON7 is a randomised, multicentre, open-label phase 3 trial. Between Dec 18, 2006, and Feb 16, 2009, after a surgical procedure aiming to debulk the disease, women with Inter…

Adultmedicine.medical_specialtyBevacizumabDrug-Related Side Effects and Adverse ReactionsAntibodies Monoclonal HumanizedDisease-Free Survivallaw.inventionchemistry.chemical_compoundRandomized controlled trialQuality of lifelawInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansAgedNeoplasm StagingOvarian NeoplasmsIntention-to-treat analysisbusiness.industryStandard treatmentArticlesMiddle Agedmedicine.diseaseCarboplatinSurgeryBevacizumabClinical trialTreatment OutcomeOncologychemistryQuality of LifeFemaleOvarian cancerbusinessmedicine.drugThe Lancet Oncology
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Does exercise intensity matter for fatigue during (neo-)adjuvant cancer treatment? The Phys-Can randomized clinical trial

2021

Exercise during cancer treatment improves cancer-related fatigue (CRF), but the importance of exercise intensity for CRF is unclear. We compared the effects of high- vs low-to-moderate-intensity exercise with or without additional behavior change support (BCS) on CRF in patients undergoing (neo-)adjuvant cancer treatment. This was a multicenter, 2x2 factorial design randomized controlled trial (Clinical Trials NCT02473003) in Sweden. Participants recently diagnosed with breast (n = 457), prostate (n = 97) or colorectal (n = 23) cancer undergoing (neo-)adjuvant treatment were randomized to high intensity (n = 144), low-to-moderate intensity (n = 144), high intensity with BCS (n = 144) or low…

MaleAnxiety030204 cardiovascular system & hematologyNeo adjuvantlaw.inventionTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicineRandomized controlled trialBehavior TherapylawNeoplasmsActivities of Daily LivingOrthopedics and Sports MedicineSjukgymnastikPhysiotherapyCancer-related fatigueLicenseFatigueDepressionCreative commonsMiddle AgedVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850Neoadjuvant TherapyExercise TherapyCancer treatmentEndurance TrainingCardiorespiratory FitnessVDP::Medisinske Fag: 700::Helsefag: 800Femalemedicine.symptomColorectal NeoplasmsPsychologybehavior change; cancer‐ related fatigue; endurance training; oncology; resistance trainingmedicine.medical_specialtyBreast NeoplasmsPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciencesmedicineHumansMuscle StrengthCancer och onkologiResistance trainingProstatic NeoplasmsResistance Training030229 sport sciencesCancer and OncologyQuality of LifeExercise intensityPhysical therapySedentary BehaviorSleep
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