0000000000217262

AUTHOR

Tiemo S. Gerber

showing 3 related works from this author

Influence of Lymphangio (L), Vascular (V), and Perineural (Pn) Invasion on Recurrence and Survival of Resected Intrahepatic Cholangiocarcinoma

2021

(1) Background: Intrahepatic cholangiocarcinoma (ICC) is a rare malignancy. Besides tumor, nodal, and metastatic status, the UICC TNM classification describes further parameters such as lymphangio- (L0/L1), vascular (V0/V1/V2), and perineural invasion (Pn0/Pn1). The aim of this study was to analyze the influence of these parameters on recurrence and survival. (2) Methods: All surgical explorations for patients with ICC between January 2008 and June 2018 were collected and further analyzed in our institutional database. Statistical analyses focused on perineural, lymphangio-, and vascular invasion examined histologically and their influence on tumor recurrence and survival. (3) Results: Of 2…

medicine.medical_specialtyPerineural invasionMalignancyGastroenterologysurvivalArticleResectionVascular invasion03 medical and health sciences0302 clinical medicineintrahepatic cholangiocarcinomaInternal medicineStatistical analysesmedicineOverall survivalvascular invasionliver surgeryIntrahepatic Cholangiocarcinomabusiness.industryRlymphangioinvasionGeneral Medicineperineural invasionmedicine.diseaseTumor recurrence030220 oncology & carcinogenesisMedicine030211 gastroenterology & hepatologybusinessJournal of Clinical Medicine
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Clinicopathological Significance of Syndecan-1 in Cholangiocarcinoma: A Study Based on Immunohistochemistry and Public Sequencing Data

2021

Background: Syndecan-1 (CD138

<i>SDC1</i>Pathologymedicine.medical_specialtyanimal structuresArticleSyndecan 1SDC103 medical and health sciences0302 clinical medicinemedicineLymph nodeIntrahepatic Cholangiocarcinoma030304 developmental biology0303 health sciencesbusiness.industryGallbladderRCancersyndecan-1General Medicinemedicine.diseasecarbohydrates (lipids)medicine.anatomical_structure030220 oncology & carcinogenesisBiliary Intraepithelial NeoplasiaMedicineImmunohistochemistrybiomarkerPancreasbusinesscholangiocarcinomaJournal of Clinical Medicine
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Liver Resection for Intrahepatic Cholangiocarcinoma—Single-Center Experience with 286 Patients Undergoing Surgical Exploration over a Thirteen Year P…

2021

Background: Intrahepatic cholangiocarcinoma (iCCA) accounts for about 10% of primary liver cancer. Surgery is the only potentially curative treatment. We report on our current series of 229 consecutive hepatic resections for iCCA, which is one of the largest Western single-center series published so far. Methods: Between January 2008 to December 2020, a total of 286 patients underwent 307 surgical explorations for intended liver resection of iCCA at our department. Data were analyzed with regard to (1) preoperative treatment of tumor, (2) operative details, (3) perioperative morbidity and mortality, (4) histopathology, (5) outcome measured by tumor recurrence, treatment of recurrence and su…

medicine.medical_specialtyProportional hazards modelbusiness.industrymedicine.medical_treatmentRGeneral MedicinePerioperativeSingle Centersurvivalrepeated liver resectionArticleSurgeryintrahepatic cholangiocarcinomaliver resectionmedicineMedicineT-stageHistopathologyHepatectomyStage (cooking)businesscholangiocarcinomaIntrahepatic CholangiocarcinomaJournal of Clinical Medicine
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