0000000000217276

AUTHOR

N. Victor Jiménez Torres

showing 4 related works from this author

Anthropometric and pharmacotherapeutic variables on acute emesis induced by cisplatin-containing chemotherapy.

2000

OBJECTIVE: To characterize the effects of anthropometric and pharmacotherapeutic variables on acute emesis induced by cisplatin-containing regimens with dosages ·50 mg·m−2. METHODS: A prospective, cross-sectional, noncontrolled study was performed to analyze acute vomiting during the first 24 hours in patients treated in a Spanish hospital. The patients received an intravenous combination of drugs (2 doses of metoclopramide 3 mg/kg, dexamethasone 20 mg) as first-choice antiemetic therapy. Intravenous ondansetron 8 mg and dexamethasone 20 mg served as an alternative regimen in patients <30 years old with a history of extrapyramidal manifestations or emesis in previous cycles. Therapeutic …

Metoclopramidemedicine.drug_classChlorpromazineMetoclopramideVomitingmedicine.medical_treatmentAntineoplastic Agents030204 cardiovascular system & hematology030226 pharmacology & pharmacyDexamethasoneOndansetron03 medical and health sciences0302 clinical medicineSex FactorsOrphenadrinemedicineAntiemeticHumansPharmacology (medical)Body Weights and MeasuresProspective StudiesDexamethasoneChemotherapybusiness.industryAge FactorsMiddle AgedPrognosisOndansetronRegimenDrug CombinationsCross-Sectional StudiesLogistic ModelsAnesthesiaAcute DiseaseMultivariate AnalysisVomitingCorticosteroidAntiemeticsmedicine.symptomCisplatinbusinessmedicine.drugThe Annals of pharmacotherapy
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Toxicity Profile and Adherence to the Pharmacotherapeutic Regimen of Gemcitabine–carboplatin in Non-small Cell Lung Cancer

2011

Objective: To analyse the relationship between doses of gemcitabine---carboplatin (GEM-CARBO) administered and incidence and level of haematological and renal toxicity, and the adherence to the treatment in patients with non-small cell lung cancer. Methods: Retrospective study, which lasted for 37 months. We were able to obtain the minimum set of data needed to carry out the follow-up with the help of Farmis-Oncofarm ® software and the medical and pharmacotherapeutic records. The haematological toxicity was assessed in accordance with the Common Toxicity Criteria 3.0. Renal toxicity was evaluated using serum creatinine levels and creatinine clearance. Results: Thirty-one patients were inclu…

medicine.medical_specialtyCreatininebusiness.industryRenal functionNeutropeniamedicine.diseaseGemcitabineCarboplatinSurgerychemistry.chemical_compoundRegimenchemistryInternal medicineToxicitymedicinebusinessLung cancermedicine.drugFarmacia Hospitalaria (English Edition)
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Pharmaceutical validation as a process of improving the quality of antineoplastic treatment

2006

Objective. To quantify the improvement added by standardization of pharmaceutical validation (PV) of antineoplastic treatment to the processes of prescription and preparation of the pharmacotherapeutic sequence, in terms of prevention and reduction of medication errors (ME). Design. Prospective cohort study during two years (from 2001-2002) for oncohaematologic patients (inpatients and outpatients) that compared the percentage of medication errors detected and resolved and the number of medication errors with potential clinical significance (severity value ≥4) intercepted during PV in both years. Results. During the PV processes, 202 ME were identified and resolved, which is the equivalent…

AdultMalemedicine.medical_specialtyTime FactorsAntineoplastic AgentsMedical Oncology030226 pharmacology & pharmacy03 medical and health sciences0302 clinical medicineInternal medicineHumansMedication ErrorsMedicinePharmacology (medical)Clinical significanceProspective StudiesMedical prescriptionProspective cohort studyAgedAged 80 and overInpatientsbusiness.industryHematologyMiddle AgedPrognosisSurgeryOncologyPharmaceutical Services030220 oncology & carcinogenesisFemalePatient CarebusinessHospital UnitsTotal Quality ManagementJournal of Oncology Pharmacy Practice
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Perfil de toxicidad y adherencia del esquema farmacoterapéutico gemcitabina-carboplatino en cáncer de pulmón no microcítico

2011

Objective: To analyse the relationship between doses of gemcitabine-carboplatin (GEM-CARBO) administered and incidence and level of haematological and renal toxicity, and the adherence to the treatment in patients with non-small cell lung cancer. Methods: Retrospective study which lasted for 37 months. We were able to obtain the minimum set of data needed to carry out the follow-up with the help of Farmis-Oncofarm® software and the medical and pharmacotherapeutic records. The haematological toxicity was assessed in accordance with the Common Toxicity Criteria 3.0. Renal toxicity was evaluated using serum creatinine levels and creatinine clearance. Results: Thirty-one patients were included …

PharmacologyCreatininemedicine.medical_specialtybusiness.industryIncidence (epidemiology)Renal functionRetrospective cohort studyCarboplatinGemcitabineSurgerychemistry.chemical_compoundRegimenchemistryInternal medicineToxicityMedicinebusinessmedicine.drugFarmacia Hospitalaria
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