0000000000219394

AUTHOR

Laurence Leenhardt

showing 2 related works from this author

2018 European Thyroid Association Guideline for the Management of Graves' Hyperthyroidism.

2018

Graves' disease (GD) is a systemic autoimmune disorder characterized by the infiltration of thyroid antigen-specific T cells into thyroid-stimulating hormone receptor (TSH-R)-expressing tissues. Stimulatory autoantibodies (Ab) in GD activate the TSH-R leading to thyroid hyperplasia and unregulated thyroid hormone production and secretion. Diagnosis of GD is straightforward in a patient with biochemically confirmed thyrotoxicosis, positive TSH-R-Ab, a hypervascular and hypoechoic thyroid gland (ultrasound), and associated orbitopathy. In GD, measurement of TSH-R-Ab is recommended for an accurate diagnosis/differential diagnosis, prior to stopping antithyroid drug (ATD) treatment and during p…

Antithyroid drugs; Graves' hyperthyroidism; Graves' orbitopathy; Management; Radioiodine therapy; Thyroidectomy;medicine.medical_specialtyendocrine systemendocrine system diseasesEndocrinology Diabetes and Metabolismmedicine.medical_treatment030209 endocrinology & metabolismGuidelinesGastroenterologyGraves' orbitopathy03 medical and health sciences0302 clinical medicineRadioiodine therapyInternal medicinemedicinePregnancyGraves' hyperthyroidismAntithyroid drugsbusiness.industryThyroidThyroidectomyAutoantibodymedicine.diseaseManagementmedicine.anatomical_structureHormone receptor030220 oncology & carcinogenesisThyroidectomyPropylthiouracilDifferential diagnosisbusinessHormonemedicine.drugEuropean thyroid journal
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European perspective on the 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroi…

2018

The American Thyroid Association (ATA) management guidelines for patients with thyroid nodules and differentiated thyroid cancer (DTC) are highly influential practice recommendations. The latest revision appeared in 2015 ("ATA 2015"). These guidelines were developed predominantly by North American experts. European experts frequently have different perspectives, given epidemiological, technological/methodological, practice organization, and medicolegal differences between the respective regions.Divergent viewpoints were the focus of an invited symposium organized by the European Association of Nuclear Medicine involving 17 European thyroidologists, four ATA Guidelines Taskforce members, and…

AdultThyroid nodulesendocrine systemmedicine.medical_specialtyendocrine system diseasesEndocrinology Diabetes and MetabolismMedizinThyroid Gland030209 endocrinology & metabolismrisk stratificationHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciences0302 clinical medicineEndocrinologyAll institutes and research themes of the Radboud University Medical CenterInternal medicineHumansMedicineThyroid NeoplasmsThyroid NoduleguidelinesDisease management (health)differentiated thyroid cancer (DTC)Thyroid cancerAdult patientsbusiness.industrythyroid nodulesPerspective (graphical)Thyroidmedicine.diseaseUnited Statesdifferentiated thyroid cancer (DTC); disease management; guidelines; pathology; risk stratification; thyroid nodules; Endocrinology Diabetes and Metabolism; EndocrinologyEuropeDiabetes and Metabolismmedicine.anatomical_structuredisease management030220 oncology & carcinogenesisPractice Guidelines as TopicRisk stratificationpathologybusiness
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