0000000000221442
AUTHOR
M. Izquierdo
showing 4 related works from this author
A comparative study of the population pharmacokinetics of gentamicin and amikacin in newborn patients
1993
SUMMARY The population kinetics of gentamicin and amikacin were studied comparatively in newborn patients with a similar range of gestation age (37.9 ± 2.9 and 36.7 ± 3.6 weeks), postnatal age (13.8 ± 7.4 and 16.7 ± 7 days) and weight (2.85 ± 0.57 and 2.72 ± 0.75 kg), undergoing routine therapeutic monitoring of their serum levels. Individual kinetic analysis of serum drug levels was done using a single-compartment model. The population model employed assumes the existence of residual variability in the serum concentrations and interindividual variability in the pharmacokinetic parameters. The clearance and the apparent distribution volume were calculated for each patient using a two-stage …
Personalized Cardiac Computational Models: From Clinical Data to Simulation of Infarct-Related Ventricular Tachycardia.
2019
In the chronic stage of myocardial infarction, a significant number of patients develop life-threatening ventricular tachycardias (VT) due to the arrhythmogenic nature of the remodeled myocardium. Radiofrequency ablation (RFA) is a common procedure to isolate reentry pathways across the infarct scar that are responsible for VT. Unfortunately, this strategy show relatively low success rates; up to 50% of patients experience recurrent VT after the procedure. In the last decade, intensive research in the field of computational cardiac electrophysiology (EP) has demonstrated the ability of three-dimensional (3D) cardiac computational models to perform in-silico EP studies. However, the personal…
Orbital origin and matrix element effects in the Ag/Si(111)-()R30° Fermi surface
2007
The Fermi surface (FS) of the Ag/Si(1 1 1)-3×3 reconstruction with an excess of Ag has been mapped by angle resolved photoemission spectroscopy with polarized light in a wide region of the reciprocal space and with different detection geometries. In contrast to previous results, a strong polarization dependence is observed. Applying the dipole selection rules, it is found that the surface state at the Fermi level, S1 state, has odd symmetry with respect to the mirror plane of the honeycomb-chained triangle structure, indicating that it is mainly derived from Ag 5px and 5py orbitals. This conclusion is revised in the new frame of a inequivalent-triangle structure for the Ag/Si(1 1 1)-3×3 at …
Buildup and structure of theInSe∕Ptinterface studied by angle-resolved photoemission and x-ray absorption spectroscopy
2006
The atomic structure and the electronic nature of the $\mathrm{In}\mathrm{Se}∕\mathrm{Pt}$ interface have been studied by x-ray absorption spectroscopy and angle-resolved photoemission, respectively. By these measurements, it has been found that Pt atoms equally incorporate into two trigonal-prismatic intralayer positions existing within the InSe layer, although, at low Pt coverage, Pt atoms seem to prefer one of these sites, where they have a lower interaction with Se atoms. The atomic structure of the $\mathrm{In}\mathrm{Se}∕\mathrm{Pt}$ interface appears to determine its electronic behavior as Pt deposition increases. At initial stages of Pt diffusion, isolated Pt atoms act as a surface …