P3‐061: Familiarity‐based recognition in multidomain amnestic and nonamnestic cognitive impaired patients: A follow‐up retest

Explorations of familiarity produced by words with specific combinations of letters

We explore familiarity-based recognition using a paradigm devised by Parkin et al. (2001). The task consists of the creation of two lists of words written with one of two different subsets of letters of the alphabet. We manipulated study time (50, 100, 200, 500 ms per word) of words with different letter probabilistic structure to those originally used by Parkin et al. Letter-based familiarity responding was robust and present even at rates producing otherwise chance performance. A second experi- ment and structural equation modelling led us to interpret the results from the point of view of a theory that takes into account the processing of similarities and differences (Hunt & MacDaniel, (…

Familiarity-based recognition in the young, healthy elderly, mild cognitive impaired and Alzheimer's patients

This study investigates the possible existence of deficits in familiarity in five samples of participants spanning a broad range of ages and cognitive states. Five groups of 16 participants with a diagnosis of multi-domain cognitive impairment with a slight or no deficit in memory, 16 multi-domain amnestic, and 16 Alzheimer's disease patients were compared in a recognition test with equivalent samples of old and young healthy participants. In one of the tests, participants studied words extracted from a restricted set of letters of the alphabet that were later mixed with new words from a different set. The unconscious use of the fluency produced by the repeated use of the set of letters was…

Recognition by familiarity is preserved in Parkinson's without dementia and Lewy-Body disease.

Objective The retrieval deficit hypothesis states that the lack of deficit in recognition often observed in patients with Parkinson's disease is because of the low retrieval requirements of the task, given that these patients have retrieval and not encoding deficits. To test this hypothesis we investigated recognition memory by familiarity in Parkinson's patients and in patients with Lewy Bodies disease and Parkinson with dementia. Method We analyzed to what extent the experimental groups were able to recognize by familiarity in a typical yes/no recognition memory task. The experimental groups were patients with early nondemented Parkinson's disease, advanced nondemented Parkinson's disease…