0000000000222204

AUTHOR

Jelena Vucetic

sj-docx-1-uix-10.1177_01617346211029656 – Supplemental material for Diagnostic Performance of Muscle Echo Intensity and Fractal Dimension for the Detection of Frailty Phenotype

Supplemental material, sj-docx-1-uix-10.1177_01617346211029656 for Diagnostic Performance of Muscle Echo Intensity and Fractal Dimension for the Detection of Frailty Phenotype by Rebeca Mirón Mombiela, Jelena Vucetic, Paloma Monllor, Jenny S. Cárdenas-Herrán, Paloma Taltavull de La Paz and Consuelo Borrás in Ultrasonic Imaging

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sj-docx-1-uix-10.1177_01617346211029656 – Supplemental material for Diagnostic Performance of Muscle Echo Intensity and Fractal Dimension for the Detection of Frailty Phenotype

Supplemental material, sj-docx-1-uix-10.1177_01617346211029656 for Diagnostic Performance of Muscle Echo Intensity and Fractal Dimension for the Detection of Frailty Phenotype by Rebeca Mirón Mombiela, Jelena Vucetic, Paloma Monllor, Jenny S. Cárdenas-Herrán, Paloma Taltavull de La Paz and Consuelo Borrás in Ultrasonic Imaging

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Muscle architecture determined by ultrasound for the diagnosis of frailty with correlation of clinical, physical and biochemical markers

La fragilidad es un síndrome clínico de mayor vulnerabilidad a factores externos que pueden desencadenar efectos adversos y llevar a la muerte. La fragilidad es prevenible y parcialmente reversible si se diagnostica a tiempo. Actualmente no existe un biomarcador cuantitativo para el diagnóstico de fragilidad. Postulamos que la ecografía muscular junto con parámetros circulantes sería buen método para identificar pacientes con riesgo de fragilidad. Se realizaron ecografías musculares del compartimento anterior del muslo en pacientes ambulatorios y se extrajeron muestras de sangre para análisis bioquímico, medición de hormonas, citocinas y parámetros del estrés oxidativo. Los pacientes se div…

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Diagnostic Performance of Muscle Echo Intensity and Fractal Dimension for the Detection of Frailty Phenotype

To determine the relationship between muscle echo intensity (EI) and fractal dimension (FD), and the diagnostic performance of both ultrasound parameters for the identification of frailty phenotype. A retrospective interpretation of ultrasound scans from a previous cohort (November 2014–February 2015) was performed. The sample included healthy participants <60 years old, and participants ≥60 divided into robust, pre-frail, and frail groups according to Fried frailty criteria. A region of interest of the rectus femoris from the ultrasound scan was segmented, and histogram function was applied to obtain EI. For fractal analysis, images were processed using two-dimensional box-counting techniq…

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Ultrasound Biomarkers for Sarcopenia: What Can We Tell So Far?

AbstractSarcopenia is a disease characterized by decreased skeletal muscle mass, strength, and loss of function that can impair quality of life and increase physical disability, adverse metabolic effects, and mortality. This review familiarizes the reader with ultrasound (US)-based biomarkers for sarcopenia with a discussion of these topics: why assessing sarcopenia is relevant for radiologists, how to evaluate muscle structure with US, the current challenges or pitfalls of these biomarkers, and the implications of all the available evidence. It summarizes the most up-to-date literature on the pathophysiology behind the use of these US-based biomarkers, the biomarkers themselves, and a prot…

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