0000000000222454

AUTHOR

B. Escat

Depth of /spl gamma/-ray interaction within continuous crystals from the width of its scintillation light-distribution

We have studied a new and inexpensive method of measuring the depth of interaction (DOI) in /spl gamma/-ray detectors with large-sized scintillation crystals. This method takes advantage of the strong correlation between the width of the undisturbed light-distribution in continuous crystals and the /spl gamma/-ray's DOI. In order to quantify the dependence of the distribution's width with respect to the DOI, we first studied an analytical model of the light-distribution and tested it by means of Monte Carlo (MC) simulations of the light transport inside the crystal. Further we present an inexpensive modification of the commonly used charge division circuit that allows analog and instantaneo…

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Assessment of a single-acquisition imaging sequence for oxygen-sensitive (3)He-MRI.

MRI of the lungs using hyperpolarized helium-3 (3He) allows the determination of intrapulmonary oxygen partial pressures (pO2). The need to separate competing processes of signal loss has hitherto required two different imaging series during two different breathing maneuvers. In this work, a new imaging strategy to measure pO2 by a single series of consecutive scans is presented. The feasibility of the method is demonstrated in three healthy human volunteers. Maps and histograms of intrapulmonary pO2 are calculated. Changes in the oxygen concentration of the inhaled gas mixture are well reproduced in the histograms. Monte Carlo (MC) simulations of the temporal evolution of 3He hyperpolariza…

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