Gene therapy with growth factors for periodontal tissue engineering : a review

The treatment of oral and periodontal diseases and associated anomalies accounts for a significant proportion of the healthcare burden, with the manifestations of these conditions being functionally and psychologically debilitating. A challenge faced by periodontal therapy is the predictable regeneration of periodontal tissues lost as a consequence of disease. Growth factors are critical to the development, maturation, maintenance and repair of oral tissues as they establish an extra-cellular environment that is conducive to cell and tissue growth. Tissue engineering principles aim to exploit these properties in the development of biomimetic materials that can provide an appropriate microen…

Oral myiasis in a cerebral palsy patient: A case report

Myiasis is a rare condition caused by the invasion of tissues by the larvae of flies, mainly from the order of Diptera. Many cases of myiasis involving various human organs have been reported. Oral Myiasis is very rare in healthy persons. It occurs mainly in the tropics and is usually associated with inadequate personal and public hygiene; sometimes accompanied by poor manual dexterity. We present a case of oral myiasis in a mentally retarded, 13- year-old boy suffering with cerebral palsy. The diagnosis was based on the characteristic clinical features and the visualization of wriggling larvae. Large numbers of larvae were found in the gingival sulcus. Treatment consisted of manual removal…

Prevalence of traumatic dental injuries and role of incisal overjet and inadequate lip coverage as risk factors among 4-15 years old government school children in Baddi-Barotiwala area, Himachal Pradesh, India

Objective: To assess the prevalence of traumatic dental injuries (TDI) in school children in Baddi- Barotiwala, Himachal Pradesh, India. Methods: A cross-sectional survey was carried out in Government schools among 1059 government school children aged 4- 15 years. The study was conducted from October 2009 to March 2010 during the school hours. The demographic detail was carried on a structured questionnaire. The data regarding the traumatic injuries was recorded using modified Ellis' classification. Results: Prevalence of TDI was found to be 4.15%. 95.45% of the injuries were to the maxillary anterior teeth. Maxillary central incisor was the most common tooth to be affected due to trauma (5…

Costochondral Grafts in the treatment of Temporomandibular joint ankylosis: a Clinical Study

Background: Treatment of temporomandibular joint (TMJ) ankylosis usually requires adequate excision of the involved ankylotic block (arthroplasty) without interposing any material (gap arthroplasty) or interpositional arthroplasty using autogenous or alloplastic materials. The objective of this paper was to note the potential of the costochondral graft (CCGs) as an interpositional material and to see whether they induce normal growth potential in the reconstructed mandible. Materials and method: The ankylosed temporomandibular joint was reached by a preauricular incision with or without angulation and exposed. In the first 4 cases, arthroplasty was done using a bur. The bony mass was detach…

17. Mainzer Allergie-Workshop