0000000000223129

AUTHOR

Andrea Ballo

showing 3 related works from this author

Study of the role of particle-particle dipole interaction in dielectrophoretic devices for biomarkers identification

2015

A three dimensional Coupled Monte Carlo-Poisson method has been used to evaluate the impact of particle-particle dipole interactions in the equilibrium distribution of a system of uncharged polarizable particles suspended in a static liquid medium under the action of an oscillating non-uniform electric field generated by polynomial electrodes. We compare the simulated distributions with experimental ones both for micro- (MDA-MB-231 breast tumor cells) and nano-(multiwall carbon nanotubes) particles. In both cases the equilibrium distributions near the electrodes are dominated by dipole interactions which locally enhance the DEP effect and promote long particles chains.

Materials scienceAnalytical chemistryLiquid mediumCarbon nanotubeMolecular physicsMDA-MB-231 breast cancer cell DEPlaw.inventionMultiwall Carbon Nanotubes Breast Tumor Cell Particle Chain Electric Field Line Initial Random DistributionDipoleDistribution (mathematics)PolarizabilitylawElectric fieldElectrodeParticle
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Theoretical and experimental study of the role of cell-cell dipole interaction in dielectrophoretic devices: application to polynomial electrodes

2013

BACKGROUND: We aimed to investigate the effect of cell-cell dipole interactions in the equilibrium distributions in dielectrophoretic devices. METHODS: We used a three dimensional coupled Monte Carlo-Poisson method to theoretically study the final distribution of a system of uncharged polarizable particles suspended in a static liquid medium under the action of an oscillating non-uniform electric field generated by polynomial electrodes. The simulated distributions have been compared with experimental ones observed in the case of MDA-MB-231 cells in the same operating conditions. RESULTS: The real and simulated distributions are consistent. In both cases the cells distribution near the elec…

ElectrophoresisPolynomialMonte Carlo methodBiomedical EngineeringCell Communication-cell-cell dipoleMolecular physicsQuantitative Biology::Cell BehaviorBiomaterialsPolarizabilityCell Line TumorElectric fieldElectric ImpedanceElectronic engineeringHumansRadiology Nuclear Medicine and imagingPoisson DistributionElectrodesPhysicsRadiological and Ultrasound TechnologyResearchGeneral MedicineDipoleElectrophoresisDistribution (mathematics)ElectrodeMonte Carlo MethodAlgorithmsBioMedical Engineering OnLine
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Theoretical and experimental study of the kinetics of particle chains near electrodes in dielectrophoretic devices

2014

Using a three dimensional coupled Monte Carlo-Poisson algorithm and experimental results we studied the role of the particle-particle dipole interaction on the kinetics of a system of human cells suspended in a static liquid medium under the action of an oscillating non-uniform electric field generated by polynomial electrodes. We found that the kinetics of the cells during negative/repulsive dielectrophoresis depends on the local distribution of particles. If the cells have generated long chains during positive/attractive dielectrophoresis, such chains can hinder subsequent detachment resulting in a reduction of the separation/manipulation efficiency of dielectrophoretic device. This effec…

Materials sciencekinetics of particle chains dielectrophoretic devicesparticle chainsKineticsElectrodeDielectrophoresisAnalytical chemistrycellsParticle chainsNanotechnologyDielectrophoresis
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