6533b832fe1ef96bd129a3a9
RESEARCH PRODUCT
Theoretical and experimental study of the kinetics of particle chains near electrodes in dielectrophoretic devices
A. La MagnaM. CamardaValentina BravatàGi ForteSilvia ScaleseLuigi MinafraGianluca GiustolisiMc GilardiBravataF. Di RaimondoFabrizio VicariMarzia PucciAlessandra RomanoS. BaldoFp CammarataAndrea BalloGiuseppe Russosubject
Materials sciencekinetics of particle chains dielectrophoretic devicesparticle chainsKineticsElectrodeDielectrophoresisAnalytical chemistrycellsParticle chainsNanotechnologyDielectrophoresisdescription
Using a three dimensional coupled Monte Carlo-Poisson algorithm and experimental results we studied the role of the particle-particle dipole interaction on the kinetics of a system of human cells suspended in a static liquid medium under the action of an oscillating non-uniform electric field generated by polynomial electrodes. We found that the kinetics of the cells during negative/repulsive dielectrophoresis depends on the local distribution of particles. If the cells have generated long chains during positive/attractive dielectrophoresis, such chains can hinder subsequent detachment resulting in a reduction of the separation/manipulation efficiency of dielectrophoretic device. This effect can be avoided by proper design of the electrodes schema.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-10-01 |