0000000000223647

AUTHOR

Tanja Pommerening

0000-0003-1584-564x

showing 5 related works from this author

Evaluating ancient Egyptian prescriptions today: Anti-inflammatory activity of Ziziphus spina-christi.

2015

Abstract Background Ziziphus spina-christi (L.) Desf. (Christ's Thorn Jujube) is a wild tree today found in Jordan, Israel, Egypt, and some parts of Africa, which was already in use as a medicinal plant in Ancient Egypt. In ancient Egyptian prescriptions, it was used in remedies against swellings, pain, and heat, and thus should have anti-inflammatory effects. Nowadays, Z. spina-christi, is used in Egypt (by Bedouins, and Nubians), the Arabian Peninsula, Jordan, Iraq, and Morocco against a wide range of illnesses, most of them associated with inflammation. Pharmacological research undertaken to date suggests that it possesses anti-inflammatory, hypoglycemic, hypotensive and anti-microbial e…

0301 basic medicinemedicine.drug_classLeupeptinsIn silicoHerbal MedicineEgypt AncientAnti-Inflammatory AgentsPharmaceutical SciencePlant RootsAnti-inflammatory03 medical and health sciencesCell Line TumorDrug DiscoveryMedicineGallocatechinBioassayHumansElectrophoretic mobility shift assayHistory AncientPharmacologyZiziphus spina-christiInflammationPlants MedicinalbiologyTraditional medicinePlant Stemsbusiness.industryPlant ExtractsTranscription Factor RelAZiziphusZiziphusbiology.organism_classificationMolecular Docking Simulation030104 developmental biologyComplementary and alternative medicineDocking (molecular)SeedsMolecular MedicinebusinessPhytomedicine : international journal of phytotherapy and phytopharmacology
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An investigation of the pharmacological applications used for the Ancient Egyptian systemic model ‘ra-ib’ compared with modern Traditional Chinese Me…

2020

Abstract Ethnopharmacological relevance Ancient Egyptian texts only offer glimpses into their conceptual understandings of the inner-body and illness manifestation. Explanations of how prescribed materia medica were believed to work are rare and obscure, often resulting in modern approximations for ancient terminology such as ‘ra-ib’—an ancient Egyptian classification predominantly translated as ‘stomach’—leading to misunderstandings of historical texts, and therefore their use of pharmacology. Aim of the study To investigate the ra-ib and the explanatory models of illness from the Egyptian perspective, and to explore the link between these and the prescribed selection of materia medica. To…

HistoryEgypt AncientMateria medicalaw.inventionTerminology03 medical and health sciences0302 clinical medicinelawDrug DiscoverySelection (linguistics)HumansRelevance (law)Medicine Chinese TraditionalHistory Ancient030304 developmental biologyPharmacopoeias as TopicPharmacology0303 health sciencesEpistemologyAncient Egyptian medicinePhilologyConceptual framework030220 oncology & carcinogenesisEthnopharmacologyMateria MedicaPharmacopoeiaDrugs Chinese Herbal
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Blunt force trauma: an exceptional example of an ancient Egyptian mummy head

2019

In the course of a scientific cooperation between the German Mummy Project at the Reiss-Engelhorn-Museen, Mannheim (Germany) and the Musée National d'Histoire et d'Art Luxembourg (Luxembourg), an ancient Egyptian mummy head was analyzed using a multidisciplinary approach including radiocarbon dating, ultra-high resolution computed tomography, physical anthropology, forensic medicine and Egyptology. Dated to the Roman Period, the mummy head belonged to an upper-class woman between 25 and 35 years of age. Computed tomography revealed a lethal blunt force trauma affecting the dorsal parts of the parietal bones, below the intact overlaying soft tissue. Moreover, ancient medical treatment was ev…

AdultHistoryMedical treatmentEgypt AncientBiological anthropologyPoison controlForensic anthropologyMummiesGeneral MedicineAncient historyWounds NonpenetratinghumanitiesHead (geology)EgyptologyBluntHomicideAnthropologyCraniocerebral TraumaHumansFemaleAnimal Science and ZoologyHeadHistory AncientEcology Evolution Behavior and SystematicsAnthropologischer Anzeiger
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In Vitro and In Vivo Antimalarial Activity Assays of Seeds from Balanites aegyptiaca: Compounds of the Extract Show Growth Inhibition and Activity ag…

2011

Balanites aegyptiaca(Balanitaceae) is a widely grown desert plant with multiuse potential. In the present paper, a crude extract fromB. aegyptiacaseeds equivalent to a ratio of 1 : 2000 seeds to the extract was screened for antiplasmodial activity. The determined IC50value for the chloroquine-susceptiblePlasmodium falciparumNF54 strain was 68.26 . Analysis of the extract by gas chromatography-mass spectrometry detected 6-phenyl-2(H)-1,2,4-triazin-5-one oxime, an inhibitor of the parasitic M18 Aspartyl Aminopeptidase as one of the compounds which is responsible for thein vitroantiplasmodial activity. The crude plant extract had a of 2.35  and showed a dose-dependent response. After depletion…

Traditional medicineArticle SubjectPlasmodium falciparumParasitemiaBiologymedicine.diseasebiology.organism_classificationAminopeptidaseIn vitrolcsh:Infectious and parasitic diseaseschemistry.chemical_compoundInfectious DiseaseschemistryIn vivoddc:570BotanymedicineParasitologylcsh:RC109-216Growth inhibitionAspartyl aminopeptidaseBalanites aegyptiacaResearch ArticleJournal of Parasitology Research
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Herbal medicinal products - Evidence and tradition from a historical perspective.

2017

Abstract Background Aside from the fully licensed herbal medicines there are products on the European pharmaceutical market which are registered by virtue of their longstanding traditional use. The normal registration procedure does not apply to them because presently they do not meet the legal requirements for a full license as set out in the relevant European Union Directive. One of these requirements, “proof of tradition”, has so far been dealt with in different ways and fails to meet the criteria of good practice. Method This analysis is based on a selective literature search in PubMed and in databases of medical and pharmaceutical history, interviews with licensing experts, a consensus…

MedizinLegislation01 natural sciencesHistory 21st Century03 medical and health sciences0302 clinical medicineDrug Discoverymedia_common.cataloged_instanceMedicineHumansddc:610European UnionEuropean unionLicensemedia_commonPharmaceutical industryPharmacologyPlants MedicinalTraditional medicinebusiness.industryHistorical ArticleHistory 20th CenturyDirectiveLegislation Drug0104 chemical sciencesProduct (business)010404 medicinal & biomolecular chemistry030220 oncology & carcinogenesisEngineering ethicsTraditional UseMedicine TraditionalPlant PreparationsbusinessPhytotherapyJournal of ethnopharmacology
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