Author: Gerd Nagel

0000000000230158

AUTHOR

Gerd Nagel

showing 2 related works from this author

Synthesis of 2-amino-6-(2-[18F]fluoro-pyridine-4-ylmethoxy)-9-(octyl-β-d-glucosyl)-purine: a novel radioligand for positron emission tomography studi…

2002

Abstract The synthesis of the novel glucose conjugated O6-methylguanine-DNA methyltransferase (MGMT) inhibitor 2-amino-6-(2-[18F]fluoro-pyridine-4-ylmethoxy)-9-(octyl-α- d -glucosyl)-purine is reported. This compound might serve as a radiotracer for the determination of the MGMT status of tumour tissue.

PurineMethyltransferasemedicine.diagnostic_testOrganic ChemistryConjugated systemBiochemistryDNA methyltransferasedigestive system diseasesTumour tissuechemistry.chemical_compoundchemistryBiochemistryPositron emission tomographyDrug DiscoveryPyridineRadioligandmedicineneoplasmsTetrahedron Letters

researchProduct

ChemInform Abstract: Synthesis of 2-Amino-6-(2- [18F] fluoro-pyridine-4-ylmethoxy)-9-(octyl-β-D-glucosyl)-purine: A Novel Radioligand for Positron Em…

2010

Purinemedicine.diagnostic_testO6-methylguanineChemistryGeneral MedicineDNA methyltransferaseTumor tissuechemistry.chemical_compoundBiochemistryPositron emission tomographyPyridinemedicineRadioligandNucleic acidChemInform

researchProduct

PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
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LSLife Sciences
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