0000000000234128

AUTHOR

Tore Tynes

showing 6 related works from this author

The INTERPHONE study: design, epidemiological methods, and description of the study population

2007

The very rapid worldwide increase in mobile phone use in the last decade has generated considerable interest in the possible health effects of exposure to radio frequency (RF) fields. A multinational case-control study, INTERPHONE, was set-up to investigate whether mobile phone use increases the risk of cancer and, more specifically, whether the RF fields emitted by mobile phones are carcinogenic. The study focused on tumours arising in the tissues most exposed to RF fields from mobile phones: glioma, meningioma, acoustic neurinoma and parotid gland tumours. In addition to a detailed history of mobile phone use, information was collected on a number of known and potential risk factors for t…

AdultMalemedicine.medical_specialtyRadio WavesEpidemiologyPopulationEpidemiological methodRisk AssessmentInterviews as Topic03 medical and health sciences0302 clinical medicineEnvironmental healthNeoplasmsEpidemiologymedicineHumans030212 general & internal medicineeducationeducation.field_of_studybusiness.industryDeveloped CountriesParotid gland tumourMiddle AgedSurgeryAcoustic neurinomaMobile phone030220 oncology & carcinogenesisEpidemiologic Research DesignCellular PhonePopulation studyFemaleRisk assessmentbusinessEpidemiologic MethodsCell PhoneEuropean Journal of Epidemiology
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The Intracranial Distribution of Gliomas in Relation to Exposure From Mobile Phones: Analyses From the INTERPHONE Study

2016

When investigating the association between brain tumors and use of mobile telephones, accurate data on tumor position are essential, due to the highly localized absorption of energy in the human brain from the radio-frequency fields emitted. We used a point process model to investigate this association using information that included tumor localization data from the INTERPHONE Study (Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden, and the United Kingdom). Our main analysis included 792 regular mobile phone users diagnosed with a glioma between 2000 and 2004. Similar to earlier results, we found a statistically significant association …

AdultMalemedicine.medical_specialtyTELEPHONENeoplasms Radiation-InducedTime FactorsEpidemiologyOriginal ContributionsTumor burdenBrain tumorAudiologyMOBILE TELEPHONES03 medical and health sciences0302 clinical medicinePhoneRisk FactorsRecall biasEXPOSITION AU RISQUECERVEAUMedicineHumans030212 general & internal medicineEpidemiologic researchSelf reportONDERADIO-FREQUENCY ELECTROMAGNETIC FIELDSbusiness.industryBrain NeoplasmsINTERPHONE STUDYMiddle Agedmedicine.diseaseTumor BurdenMobile phone030220 oncology & carcinogenesisEpidemiologic Research DesignGLIOMAFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieSPATIAL POINT PATTERNNeoplasm GradingbusinessINTRACRANIAL DISTRIBUTIONCell PhoneTUMEUR
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Validation of short term recall of mobile phone use for the Interphone study

2006

Aim: To validate short term recall of mobile phone use within Interphone, an international collaborative case control study of tumours of the brain, acoustic nerve, and salivary glands related to mobile telephone use. Methods: Mobile phone use of 672 volunteers in 11 countries was recorded by operators or through the use of software modified phones, and compared to use recalled six months later using the Interphone study questionnaire. Agreement between recalled and actual phone use was analysed using both categorical and continuous measures of number and duration of phone calls. Results: Correlations between recalled and actual phone use were moderate to high (ranging from 0.5 to 0.8 acros…

Observer Variationmedicine.medical_specialtyRecallbusiness.industryPublic Health Environmental and Occupational HealthReproducibility of ResultsAudiologyTerm (time)SurgeryCohen's kappaPhoneMobile phoneCase-Control StudiesMental RecallHumansMedicineOriginal ArticleGeometric meanbusinessCategorical variableCell PhoneKappaOccupational and Environmental Medicine
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Diagnostic radiological examinations and risk of intracranial tumours in adults—findings from the Interphone Study

2021

Abstract Background Exposure to high doses of ionizing radiation is among the few well-established brain tumour risk factors. We used data from the Interphone study to evaluate the effects of exposure to low-dose radiation from diagnostic radiological examinations on glioma, meningioma and acoustic neuroma risk. Methods Brain tumour cases (2644 gliomas, 2236 meningiomas, 1083 neuromas) diagnosed in 2000–02 were identified through hospitals in 13 countries, and 6068 controls (population-based controls in most centres) were included in the analysis. Participation across all centres was 64% for glioma cases, 78% for meningioma cases, 82% for acoustic neuroma cases and 53% for controls. Informa…

Adultmedicine.medical_specialtyionizingEpidemiologyPopulationAcoustic neuromameningiomaacousticMeningioma03 medical and health sciences0302 clinical medicineIsotopesRisk FactorsgliomaGliomaMeningeal Neoplasmsotorhinolaryngologic diseasesHumansMedicineeducationeducation.field_of_studyRadiationmedicine.diagnostic_testBrain Neoplasmsbusiness.industryNeuroma AcousticGeneral MedicineOdds ratiomedicine.diseaseNeuromastudies3. Good health3141 Health care scienceCase-Control Studies030220 oncology & carcinogenesisneuromaRadiologybusinessCell Phonecase-control030217 neurology & neurosurgeryCerebral angiographyComputed tomography of the headInternational Journal of Epidemiology
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A Pooled Analysis of Extremely Low-Frequency Magnetic Fields and Childhood Brain Tumors

2010

Pooled analyses may provide etiologic insight about associations between exposure and disease. In contrast to childhood leukemia, no pooled analyses of childhood brain tumors and exposure to extremely low-frequency magnetic fields (ELF-MFs) have been conducted. The authors carried out a pooled analysis based on primary data (1960–2001) from 10 studies of ELF-MF exposure and childhood brain tumors to assess whether the combined results, adjusted for potential confounding, indicated an association. The odds ratios for childhood brain tumors in ELF-MF exposure categories of 0.1–<0.2 μT, 0.2–<0.4 μT, and ≥0.4 μT were 0.95 (95% confidence interval: 0.65, 1.41), 0.70 (95% CI: 0.40, 1.22), and 1.1…

Oncologymedicine.medical_specialtyNeoplasms Radiation-InducedChildhood leukemiaEpidemiologyBrain tumorGlobal HealthCentral nervous system diseaseElectromagnetic FieldsRisk FactorsInternal medicineEpidemiologymedicineHumansChildBrain Neoplasmsbusiness.industryIncidenceConfoundingOdds ratiomedicine.diseaseConfidence intervalSurgeryMeta-analysisbusinessSystematic Reviews and Meta- and Pooled AnalysesAmerican Journal of Epidemiology
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Location of Gliomas in Relation to Mobile Telephone Use: A Case-Case and Case-Specular Analysis

2011

The energy absorbed from the radio-frequency fields of mobile telephones depends strongly on distance from the source. The authors' objective in this study was to evaluate whether gliomas occur preferentially in the areas of the brain having the highest radio-frequency exposure. The authors used 2 approaches: In a case-case analysis, tumor locations were compared with varying exposure levels; in a case-specular analysis, a hypothetical reference location was assigned for each glioma, and the distances from the actual and specular locations to the handset were compared. The study included 888 gliomas from 7 European countries (2000-2004), with tumor midpoints defined on a 3-dimensional grid …

AdultMalemedicine.medical_specialtyTime FactorsAdolescentRadio Wavesglioma; cellular phone; brain neoplasms; telephoneEpidemiologyLogistic regressionHandsetMobile telephonelaw.invention03 medical and health sciences0302 clinical medicineRisk FactorslawParietal LobegliomaGliomaStatisticsHumansMedicine030212 general & internal medicineSpecular reflectionAgedRetrospective Studiesbrain neoplasmsbusiness.industryMiddle Agedmedicine.diseaseGrid basedTemporal LobeFrontal LobeSurgeryEuropeLogistic ModelsResearch DesignMobile phonecellular phone030220 oncology & carcinogenesisFemaletelephoneConditional logistic regressionOccipital LobebusinessCell PhoneAmerican Journal of Epidemiology
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