0000000000234722

AUTHOR

F. Nociforo

showing 5 related works from this author

Successful control of an outbreak of colonization by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae sequence type 258 in a neonatal inte…

2013

This article reports an outbreak of colonization by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) sequence type (ST) 258 in a neonatal intensive care unit (NICU) in Palermo, Italy. KPC-Kp ST258 was detected by an active surveillance culture programme. Between 18th September and 14th November 2012, KPC-Kp was isolated from 10 out of 54 neonates admitted in the outbreak period. No cases of infection were recorded. Male sex was associated with colonization, whereas administration of ampicilline-sulbactam plus gentamicin was protective. Infection control interventions interrupted the spread of KPC-Kp without the need to close the NICU to new admissions. (C) 2013 The Healt…

ColonizationMaleMicrobiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaPediatricsmedicine.medical_specialtyNeonatal intensive care unitKlebsiella pneumoniaeMultidrug resistanceSettore MED/42 - Igiene Generale E ApplicataST258beta-LactamasesDisease OutbreaksNeonatal intensive care unitSettore MED/38 - Pediatria Generale E SpecialisticaBacterial ProteinsDrug Resistance Multiple BacterialIntensive Care Units NeonatalAmpicillinpolycyclic compoundsmedicineHumansInfection controlColonizationInfection ControlKPC-Klebsiella pneumoniaebiologybusiness.industryInfant NewbornOutbreakGeneral MedicineSulbactambiochemical phenomena metabolism and nutritionbacterial infections and mycosesbiology.organism_classificationKlebsiella InfectionsKlebsiella pneumoniaeInfectious DiseasesItalyFemaleGentamicinbusinessMultilocus Sequence Typingmedicine.drugJournal of Hospital Infection
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Outbreak of colonizations by extended-spectrum β-lactamase-producing Escherichia coli sequence type 131 in a neonatal intensive care unit, Italy

2013

Abstract Background Extended spectrum β-lactamases (ESBLs) often associated with resistance to aminoglycosides and fluoroquinolones have recently emerged in community-associated Escherichia coli. The worldwide clonal dissemination of E. coli sequence type (ST)131 is playing a prominent role. We describe an outbreak of colonizations by ESBL-producing E. coli (ESBL-E. coli) in the neonatal intensive care unit (NICU) of the University Hospital, Palermo, Italy. Methods An epidemiological investigation was conducted with the support of molecular typing. All children admitted to the NICU and colonized by ESBL-E. coli between January and June 2012, were included in the study. Cases were defined as…

Microbiology (medical)NICUmedicine.medical_specialtyNeonatal intensive care unitST131business.industryTransmission (medicine)EpidemiologyResearchPublic Health Environmental and Occupational HealthOutbreakDrug resistancemedicine.disease_causeMicrobiologyInfectious DiseasesMedical microbiologyEpidemiologymedicineInfection controlmulti-drug resistance E.coli ESBLPharmacology (medical)ESBL-Escherichia colibusinessEscherichia coliAntimicrobial Resistance and Infection Control
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Esophageal atresia in newborns: a wide spectrum from the isolated forms to a full VACTERL phenotype?

2013

Background: VATER association was first described in 1972 by Quan and Smith as an acronym which identifies a non-random co-occurrence of Vertebral anomalies, Anal atresia, Tracheoesophageal fistula and/or Esophageal atresia, Radial dysplasia. It is even possible to find out Cardiovascular, Renal and Limb anomalies and the acronym VACTERL was adopted, also, embodying Vascular, as single umbilical artery, and external genitalia anomalies. Methods: Data on patients with esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) admitted in the Neonatal Intensive Care Unit (NICU) between January 2003 and January 2013 were evaluated for the contingent occurrence of typical VACTERL a…

Heart Defects CongenitalMalemedicine.medical_specialtyPediatricsVATERLimb Deformities CongenitalAnal CanalTracheoesophageal fistulaKidneyNervous System MalformationsUmbilical ArteriesAssociationAnus ImperforateEsophagusSettore MED/38 - Pediatria Generale E SpecialisticaIntensive Care Units NeonatalVACTERLmedicinePrevalenceHumansEsophagusEsophageal AtresiaSicilyRetrospective StudiesCongenital malformationsSingle umbilical arterybusiness.industryTracheo-esophageal fistulaResearchSettore MED/20 - Chirurgia Pediatrica E InfantileRadial dysplasiaInfant NewbornAnomaliesSyndromeAnal canalToesmedicine.diseaseVACTERL associationSpineSurgeryTracheaEsophageal atresia; Tracheo-esophageal fistula; VATER; VACTERL; Association; Congenital malformations; Anomaliesmedicine.anatomical_structureAnal atresiaPhenotypeAtresiaCongenital malformationFemalebusiness
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Circolazione di MRSA in età pediatrica in ambiente ospedaliero e in comunità

2013

Introduzione. Negli ultimi anni si è assistito ad un generale incremento e ad una sempre più estesa diffusione, sia in ambito ospedaliero che comunitario, di microrganismi multiresistenti. In assenza ed in attesa di trattamenti farmacologici efficaci maggiore attenzione deve essere impiegata alla realizzazione di strategie di sorveglianza mirate. Il primo isolamento di un ceppo di Staphylococcus aureus meticillinoresistente (MRSA) risale al 1961 e fu seguito da una repentina diffusione negli ospedali di tutto il mondo. Ad oggi MRSA è riconosciuto come uno dei principali agenti responsabili delle infezioni nosocomiali e le percentuali di isolamento variano da Paese in Paese in maniera notevo…

MRSA sorveglianza antibiotico resistenza
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Epidemic spread of ST1-MRSA-IVa in a neonatal intensive care unit, Italy

2012

Abstract Background Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has recently emerged as an important pathogen in neonatal intensive care units (NICUs). The purposes of this study were to characterize methicillin-resistant isolates from an outbreak in a NICU, to examine the genetic traits and clonality of CA-MRSA, and to review the characteristics and outcomes of the neonatal cases and investigate the routes of entry and transmission of the MRSA outbreak strain in the NICU under study. Methods The study NICU practiced an active surveillance program for multidrug-resistant organisms, including weekly cultures for detection of MRSA from nasal swabs among all the …

NICUMaleMethicillin-Resistant Staphylococcus aureusPediatricsmedicine.medical_specialtyMRSA intensive care unitNeonatal intensive care unitEpidemiologyCA-MRSAMicrobial Sensitivity Testsmedicine.disease_causeStaphylococcal infectionslaw.inventionDisease OutbreakslawIntensive careIntensive Care Units NeonatalmedicineInfection controlHumansPediatrics Perinatology and Child HealthCross InfectionInfection ControlTransmission (medicine)business.industrylcsh:RJ1-570Infant NewbornOutbreaklcsh:PediatricsStaphylococcal Infectionsmedicine.diseaseIntensive care unitMethicillin-resistant Staphylococcus aureusBacterial Typing TechniquesCommunity-Acquired InfectionsItalyPediatrics Perinatology and Child HealthEmergency medicineFemalebusinessResearch ArticleBMC Pediatrics
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