0000000000235021
AUTHOR
Juan Llopis-morales
sj-docx-1-aut-10.1177_13623613211039950 – Supplemental material for Systematic review of prenatal exposure to endocrine disrupting chemicals and autism spectrum disorder in offspring
Supplemental material, sj-docx-1-aut-10.1177_13623613211039950 for Systematic review of prenatal exposure to endocrine disrupting chemicals and autism spectrum disorder in offspring by Salvador Marí-Bauset, Isabel Peraita-Costa, Carolina Donat-Vargas, Agustín Llopis-González, Amelia Marí-Sanchis, Juan Llopis-Morales and María Morales Suárez-Varela in Autism
Endocrine Disruptors and Autism Spectrum Disorder in Pregnancy: A Review and Evaluation of the Quality of the Epidemiological Evidence
Exposure to environmental contaminants during pregnancy has been linked to adverse health outcomes later in life. Notable among these pollutants are the endocrine disruptors chemicals (EDCs), which are ubiquitously present in the environment and they have been measured and quantified in the fetus. In this systematic review, our objective was to summarize the epidemiological research on the potential association between prenatal exposure to EDCs and Autism Spectrum Disorder (ASD) published from 2005 to 2016. The Navigation Guide Systematic Review Methodology was applied. A total of 17 studies met the inclusion criteria for this review, including: five cohorts and 12 case-control. According t…
Systematic review of prenatal exposure to endocrine disrupting chemicals and autism spectrum disorder in offspring.
Epidemiological studies, which can have inherent methodological limitations, are used to study the relation between endocrine disrupting chemicals and autism spectrum disorder. The objective is to systematically review the treatment of methodological limitations and assess the quality and strength of the findings in the available literature. The quality and strength of the evidence were evaluated using the Navigation Guide Systematic Review Methodology. The overall quality and strength of the available studies were “moderate” and “limited,” respectively. Risk of bias due to the methodological limitations regarding the exclusion of potential confounding factors and the lack of accuracy of e…