0000000000235310

AUTHOR

Marina Lacasaña

showing 7 related works from this author

A systematic review of neurodevelopmental effects of prenatal and postnatal organophosphate pesticide exposure

2014

Agricultural and residential use of organophosphate (OP) pesticides has increased in recent decades after banning some persistent pesticides. Although there is evidence of the effects of OPs on neurodevelopment and behaviour in adults, limited information is available about their effects in children, who might be more vulnerable to neurotoxic compounds. This paper was aimed at analysing the scientific evidence published to date on potential neurodevelopmental and behavioural effects of prenatal and postnatal exposure to OPs. A systematic review was undertaken to identify original articles published up to December 2012 evaluating prenatal or postnatal exposure to OPs in children and effects …

Mental developmentMalemedicine.medical_specialtyChild Behaviorprenatal exposureToxicologyToxicologychemistry.chemical_compoundAttention ProblemsChild DevelopmentFetusPregnancyEnvironmental healthEpidemiologyGenetic predispositionMedicineHumansPesticidesAdverse effectChildPrenatal exposurePsychomotor learningorganophosphorus pesticidesneurodevelopmentbusiness.industryOrganophosphateBrainGeneral MedicineEnvironmental ExposureOrganophosphateschemistryFemalepostnatal exposurebusiness
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Placental DNA methylation signatures of maternal smoking during pregnancy and potential impacts on fetal growth.

2021

We would like to thank all the families that participated in these studies for their generous contribution. Detailed acknowledgements and funding can be found in Sup plementary Material.

EpigenomicsMaternal smokingPlacentaGeneral Physics and AstronomyReproductive health and childbirthBioinformaticsLow Birth Weight and Health of the NewbornEpigenesis GeneticFetal DevelopmentPregnancyInfant MortalityFetal growth2.1 Biological and endogenous factorsAetiologyPediatricMultidisciplinaryQSmokingCord bloodDNA methylationEpigeneticsFemalemedicine.symptomScience1.1 Normal biological development and functioningInflammationFetus -- Trastorns del creixementBiologyGeneral Biochemistry Genetics and Molecular BiologyArticleGenetic HeterogeneityGeneticPretermUnderpinning researchTobaccomedicineGeneticsHumansEpigeneticsConditions Affecting the Embryonic and Fetal PeriodsNucleotide MotifsPregnancyHormone activitydNaMGeneral ChemistryEpigenomeDNA MethylationPerinatal Period - Conditions Originating in Perinatal Periodmedicine.diseaseEmbarassades -- Consum de tabacGood Health and Well BeingRisk factorsEpigenesis
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Chronic burden of near-roadway traffic pollution in 10 European cities (APHEKOM network).

2013

AD; International audience; Recent epidemiological research suggests that near road traffic-related pollution may cause chronic disease, as well as exacerbate related pathologies, implying that the entire “chronic disease progression” should be attributed to air pollution, no matter what the proximate cause was. We estimated the burden of childhood asthma attributable to air pollution in 10 European cities by calculating the number of cases of 1) asthma caused by near road traffic-related pollution, and 2) acute asthma events related to urban air pollution levels. We then expanded our approach to include coronary heart diseases in adults.Derivation of attributable cases required combining c…

Pulmonary and Respiratory MedicinePollutionAdultPediatricsmedicine.medical_specialtyExacerbationmedia_common.quotation_subjectSloveniaAir pollutionCoronary Disease010501 environmental sciencesmedicine.disease_cause01 natural sciencesRisk Assessment[SHS]Humanities and Social Sciences03 medical and health sciences0302 clinical medicineEnvironmental healthAir Pollution11. SustainabilityEpidemiologyMedicineHumans030212 general & internal medicineCitiesChildEconomie quantitative0105 earth and related environmental sciencesAsthmamedia_commonVehicle EmissionsPollutantSwedenInhalation Exposurebusiness.industryPublic healthmedicine.disease[SHS.ECO]Humanities and Social Sciences/Economics and FinanceAsthma3. Good healthItaly13. Climate actionSpainAustriabusinessRisk assessmentEnvironmental MonitoringThe European respiratory journal
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Socioeconomic Factors and the Risk of Anencephaly in a Mexican Population: A Case-Control Study

2005

Objective. The study was designed to evaluate the association between socioeconomic level (as measured by maternal education, maternal occupation, and monthly family income) and anencephaly. Methods. The authors conducted a case-control study using data from the Epidemiological Surveillance System Register for Neural Tube Defects for three states of the Mexican Republic: Puebla, Guerrero and the State of Mexico. Mothers of 151 cases of infants born with anencephaly and mothers of 151 control infants born during the period March 2000 to February 2001 were interviewed about their socioeconomic characteristics and other factors including reproductive history, use of prenatal care, use of tobac…

AdultPediatricsmedicine.medical_specialtyAdolescentMatched-Pair AnalysisMothersFamily incomeEducation03 medical and health sciences0302 clinical medicineRisk FactorsAnencephalymedicineHumans030212 general & internal medicineOccupationsRisk factorMexicoSocioeconomic statusAnencephaly030505 public healthbusiness.industryPublic healthInfant NewbornPublic Health Environmental and Occupational HealthCase-control studymedicine.diseaseMexican populationMaternal educationSocioeconomic FactorsCase-Control StudiesIncomeEducational StatusFemale0305 other medical sciencebusinessResearch ArticleDemographyPublic Health Reports
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Air pollution exposure during pregnancy and reduced birth size: a prospective birth cohort study in Valencia, Spain

2010

Abstract Background Maternal exposure to air pollution has been related to fetal growth in a number of recent scientific studies. The objective of this study was to assess the association between exposure to air pollution during pregnancy and anthropometric measures at birth in a cohort in Valencia, Spain. Methods Seven hundred and eighty-five pregnant women and their singleton newborns participated in the study. Exposure to ambient nitrogen dioxide (NO2) was estimated by means of land use regression. NO2 spatial estimations were adjusted to correspond to relevant pregnancy periods (whole pregnancy and trimesters) for each woman. Outcome variables were birth weight, length, and head circumf…

medicine.medical_specialtyEmbarazoBirth weightHealth Toxicology and MutagenesisNitrogen Dioxidelcsh:RC963-969PregnancyEstudios prospectivosmedicine:Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants::Air Pollutants [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure::Maternal Exposure [Medical Subject Headings]Birth WeightBody SizeHumansContaminantes del aireProspective StudiesProspective cohort study:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]Vehicle Emissions:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]PregnancyAir PollutantsInhalation Exposurebusiness.industryObstetricslcsh:Public aspects of medicineResearchPublic Health Environmental and Occupational HealthInfant Newbornlcsh:RA1-1270Odds ratioAnthropometrymedicine.disease:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Prospective Studies [Medical Subject Headings]Exposición maternaMaternal ExposureSpainCohortInfant Small for Gestational Agelcsh:Industrial medicine. Industrial hygieneSmall for gestational ageFemaleValenciabusinessCohort studyEnvironmental Monitoring
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Parental occupational exposure to organic solvents and anencephaly in Mexico

2009

Objective: To assess the relationship between parental occupational exposure to organic solvents, and the risk of anencephaly in Mexico. Methods: A case-control study was conducted based on the registers of the Epidemiological Surveillance System for Neural Tube Defects in Mexico; 151 cases of anencephaly of ≥20 weeks’ gestation were included. A control, born alive and without any apparent congenital malformations at birth, was selected for each case in the same maternity service in which the case was born. Information on occupational exposures, lifestyle habits, reproductive history, use of medicines, supplementation with multivitamins and folic acid, was obtained by a general questionnair…

AdultMalemedicine.medical_specialtyExposición profesional:Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::Solvents [Medical Subject Headings]Logistic regressionOccupational safety and healthOccupational medicineRisk FactorsOccupational ExposureEnvironmental healthAnencephaly:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure::Maternal Exposure [Medical Subject Headings]:Diseases::Congenital Hereditary and Neonatal Diseases and Abnormalities::Congenital Abnormalities::Abnormalities Severe Teratoid::Anencephaly [Medical Subject Headings]medicineHumansMexicoAnencephalyPregnancybusiness.industryPublic Health Environmental and Occupational Health:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure::Occupational Exposure [Medical Subject Headings]Odds ratioOccupational exposureAnencefaliamedicine.diseaseSolventesSurgeryB vitamins:Geographicals::Geographic Locations::Americas::North America::Mexico [Medical Subject Headings]Maternal ExposureCase-Control StudiesPaternal ExposureSolventsGestationFemalebusinessOccupational and Environmental Medicine
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Maternal and paternal occupational exposure to agricultural work and the risk of anencephaly.

2006

Aims: To evaluate the association between parental occupational exposure to agricultural work and the risk of anencephaly in three Mexican states. Methods: A paired case control study (1:1) was done based on records of the Epidemiological Surveillance System of Neural Tube Defects in Mexico; 151 cases of anencephaly of more than 20 weeks’ gestation were selected between March 2000 and February 2001. Controls were selected from the same maternity services as those of the cases and were born alive without congenital malformations. Information was obtained from both parents by means of a general questionnaire, a food frequency questionnaire, and a specific questionnaire on occupational exposur…

AdultMalemedicine.medical_specialtyAdolescentRisk AssessmentOccupational medicineFolic AcidPregnancyOccupational ExposureSurveys and QuestionnairesAnencephalyEpidemiologymedicineOdds RatioHumansRisk factorPesticidesMexicoPregnancyAnencephalyObstetricsbusiness.industryPublic Health Environmental and Occupational HealthCase-control studyAgricultureOdds ratioMiddle Agedmedicine.diseaseSurgeryMaternal ExposureCase-Control StudiesPaternal ExposureFemaleOriginal ArticleRisk assessmentbusinessOccupational and environmental medicine
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