0000000000237806

AUTHOR

Frédérique Debomy

showing 3 related works from this author

Low preoperative cholesterol level is a risk factor of sepsis and poor clinical outcome in patients undergoing cardiac surgery with cardiopulmonary b…

2014

Systemic inflammatory response syndrome and sepsis frequently occur after cardiac surgery with cardiopulmonary bypass. The aim of the present study was to investigate whether preoperative cholesterol levels can predict sepsis onset and postoperative complications in patients undergoing cardiac surgery with cardiopulmonary bypass.Prospective observational study.Surgical ICU of a French university hospital.Two hundred and seventeen consecutive patients older than 18 years admitted for planned cardiac surgery with cardiopulmonary bypass.Measurements of plasma blood lipids and inflammation markers before anesthesia induction (baseline), at cardiopulmonary bypass start, at cardiopulmonary bypass…

CalcitoninMalemedicine.medical_specialtyCritical CareCalcitonin Gene-Related PeptideLipoproteinsInflammationCritical Care and Intensive Care Medicinelaw.inventionSepsisPostoperative ComplicationslawRisk FactorsInternal medicineSepsisCardiopulmonary bypassMedicineHumansProspective StudiesRisk factorCardiac Surgical ProceduresProtein PrecursorsProspective cohort studyAgedCardiopulmonary Bypassbusiness.industryMiddle Agedmedicine.diseaseSystemic Inflammatory Response SyndromeCardiac surgerySystemic inflammatory response syndromeCholesterolLogistic ModelsTreatment OutcomeElective Surgical ProceduresArea Under CurveCardiologyCytokinesFemalemedicine.symptombusinessElective Surgical ProcedureBiomarkersCritical care medicine
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Care management in a French cohort with Down syndrome from the AnDDI-Rares/CNSA study.

2021

Down syndrome (DS) is a genetic neurodevelopmental disorder. In individuals with DS, a multidisciplinary approach to care is required to prevent multiple medical complications. The aim of this study was to describe the rehabilitation, medical care, and educational and social support provided to school-aged French DS patients with varying neuropsychological profiles. A mixed study was conducted. Quantitative data were obtained from a French multicentre study that included patients aged 4-20 years with diverse genetic syndromes. Qualitative data were collected by semi-structured face-to-face interviews and focus groups. Ninety-five DS subjects with a mean age of 10.9 years were included. Sixt…

Occupational therapyMalemedicine.medical_specialtyDown syndromeAdolescentWaiting Listsmedicine.medical_treatmentHealth Services Accessibility03 medical and health sciencesSocial supportYoung Adult0302 clinical medicineIntellectual disabilityGeneticsmedicineHumansChildGenetics (clinical)030304 developmental biologyPsychomotor learning0303 health sciencesRehabilitationbusiness.industryMultidisciplinary careNeurological RehabilitationSocial SupportGeneral Medicinemedicine.diseaseFocus group3. Good healthEducation of Intellectually DisabledPatient Care ManagementEducational supportFamily medicineChild PreschoolCohortIntellectual deficiencyFemaleInterdisciplinary CommunicationFranceDown Syndromebusiness030217 neurology & neurosurgery[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyEuropean journal of medical genetics
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Associations between cognitive performance and the rehabilitation, medical care and social support provided to French children with Prader-Willi synd…

2020

International audience; Prader-Willi syndrome (PWS) is a rare genetic neurodevelopmental disorder with a characteristic behavioural phenotype. A multidisciplinary approach to care is required to prevent multiple medical complications in individuals affected by PWS. The aim of this study was to describe the rehabilitation, medical care, educational and social support provided to school-aged French PWS patients with varying neuropsychological profiles. Data were obtained from a French multicentre study that included patients aged 4-20 years with diverse genetic syndromes. Nineteen PWS subjects with a mean age of 9.2 years were included. The mean full-scale intellectual quotient (IQ) was 58 (W…

Male0301 basic medicinemedicine.medical_treatmentIntellectual disabilityMESH: CognitionCBCL030105 genetics & heredityCognitionMultidisciplinary approachMESH: ChildIntellectual disabilityMedicineChildGenetics (clinical)RehabilitationMESH: Hormone Replacement TherapyNeurological RehabilitationNeuropsychologyWechsler Adult Intelligence ScaleGeneral Medicine3. Good healthMESH: Young AdultChild PreschoolEducation SpecialFemaleFrancePrader-Willi SyndromeOccupational therapymedicine.medical_specialtyAdolescentHormone Replacement TherapyMESH: Social Support[SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human geneticsYoung Adult03 medical and health sciencesSocial supportMESH: Neurological RehabilitationGeneticsHumansPsychiatryMESH: AdolescentMESH: Humansbusiness.industryMESH: Child PreschoolSocial Supportmedicine.diseaseMESH: MaleMESH: FrancePatient care management030104 developmental biologyMESH: Education Special[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsMESH: Prader-Willi SyndromebusinessMESH: FemaleEuropean Journal of Medical Genetics
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