0000000000239936
AUTHOR
Pēteris Ručevskis
Application of Graph Clustering and Visualisation Methods to Analysis of Biomolecular Data
In this paper we present an approach based on integrated use of graph clustering and visualisation methods for semi-supervised discovery of biologically significant features in biomolecular data sets. We describe several clustering algorithms that have been custom designed for analysis of biomolecular data and feature an iterated two step approach involving initial computation of thresholds and other parameters used in clustering algorithms, which is followed by identification of connected graph components, and, if needed, by adjustment of clustering parameters for processing of individual subgraphs.
A Potential Field Function for Overlapping Point Set and Graph Cluster Visualization
In this paper we address the problem of visualizing overlapping sets of points with a fixed positioning in a comprehensible way. A standard visualization technique is to enclose the point sets in isocontours generated by bounding a potential field function. The most commonly used functions are various approximations of the Gaussian distribution. Such an approach produces smooth and appealing shapes, however it may produce an incorrect point nesting in generated regions, e.g. some point is contained inside a foreign set region. We introduce a different potential field function that keeps the desired properties of Gaussian distribution, and in addition guarantees that every point belongs to a…