0000000000239988

AUTHOR

E. Jantus Lewintre

showing 5 related works from this author

1035P Effect of gut microbiota on immunotherapy of advanced NSCLC

2020

Oncologybiologybusiness.industrymedicine.medical_treatmentImmunologymedicineHematologyImmunotherapyGut florabiology.organism_classificationbusinessAnnals of Oncology
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62P Novel therapeutic strategies in NSCLC: Lung-tumorspheres as an effective in vitro screening platform

2016

Pulmonary and Respiratory MedicineLungmedicine.anatomical_structureOncologybusiness.industryCancer researchMedicinebusinessIn vitroJournal of Thoracic Oncology
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Prevalence and clinical association of gene mutations through multiplex mutation testing in patients with NSCLC

2017

[EN] Background Reported prevalence of driver gene mutations in non-small-cell lung cancer (NSCLC) is highly variable and clinical correlations are emerging. Using NSCLC biomaterial and clinical data from the European Thoracic Oncology Platform Lungscape iBiobank, we explore the epidemiology of mutations and association to clinicopathologic features and patient outcome (relapse-free survival, time-to-relapse, overall survival). Methods Clinically annotated, resected stage I¿III NSCLC FFPE tissue was assessed for gene mutation using a microfluidics-based multiplex PCR platform. Mutant-allele detection sensitivity is¿>1% for most of the ~150 (13 genes) mutations covered in the multiplex test.…

0301 basic medicineOncologyMaleLung NeoplasmsDNA Mutational AnalysisKRAS MUTATIONSGene mutationmedicine.disease_cause0302 clinical medicinemultiplex mutation analysisCarcinoma Non-Small-Cell LungMultiplex mutation analysisPrevalenceMultiplexAnaplastic Lymphoma KinaseHETEROGENEITYAged 80 and overMutationSmokingHematologyMiddle AgedProto-Oncogene Proteins c-metProgression-Free SurvivalOncology030220 oncology & carcinogenesisAdenocarcinomaFemaleKRASPREDICT SURVIVALAdultmedicine.medical_specialtyEGFRCELL LUNG-CANCERPrognosis molecular stagingprognosis molecular stagingEGFR KRAS PIK3CAVALIDATION03 medical and health sciencesYoung AdultInternal medicineMultiplex polymerase chain reactionmedicineKRASTYROSINE KINASE INHIBITORSHumansProgression-free survivalLung cancerAgedNeoplasm Stagingbusiness.industryMICROBIOLOGIAADENOCARCINOMAAMPLIFICATIONPIK3CAmedicine.disease030104 developmental biologynon-small-cell lung cancerMutationOVEREXPRESSIONbusinessMultiplex Polymerase Chain ReactionNon-small-cell lung cancerAnnals of Oncology
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1063P Profiling of peripheral T cell receptor beta chain repertoire in non-small cell lung cancer (NSCLC) patients treated with anti-PD1

2020

Oncologybusiness.industryRepertoireCancer researchmedicinenon-small cell lung cancer (NSCLC)HematologyT-Cell Receptor Beta ChainAnti pd1medicine.diseasebusinessPeripheralAnnals of Oncology
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1212P Exosomes cargo analysis as an approach to identify new biomarkers in NSCLC

2020

Oncologybusiness.industryCancer researchMedicineHematologybusinessMicrovesiclesAnnals of Oncology
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