1035P Effect of gut microbiota on immunotherapy of advanced NSCLC

62P Novel therapeutic strategies in NSCLC: Lung-tumorspheres as an effective in vitro screening platform

Prevalence and clinical association of gene mutations through multiplex mutation testing in patients with NSCLC

[EN] Background Reported prevalence of driver gene mutations in non-small-cell lung cancer (NSCLC) is highly variable and clinical correlations are emerging. Using NSCLC biomaterial and clinical data from the European Thoracic Oncology Platform Lungscape iBiobank, we explore the epidemiology of mutations and association to clinicopathologic features and patient outcome (relapse-free survival, time-to-relapse, overall survival). Methods Clinically annotated, resected stage I¿III NSCLC FFPE tissue was assessed for gene mutation using a microfluidics-based multiplex PCR platform. Mutant-allele detection sensitivity is¿>1% for most of the ~150 (13 genes) mutations covered in the multiplex test.…

1063P Profiling of peripheral T cell receptor beta chain repertoire in non-small cell lung cancer (NSCLC) patients treated with anti-PD1

1212P Exosomes cargo analysis as an approach to identify new biomarkers in NSCLC