0000000000241811
AUTHOR
Monica Lamberti
showing 4 related works from this author
Phase II trial of bevacizumab and dose/dense chemotherapy with cisplatin and metronomic daily oral etoposide in advanced non-small-cell-lung cancer p…
2011
Bevacizumab, is a humanized monoclonal antibody to vasculo-endothelial- growth-factor, with anticancer activity in non-small-cell-lung cancer (NSCLC) patients. Our previous results from a dose/finding phase I trial in NSCLC patients, demonstrated the anti-angiogenic effects and toxicity of a newest bevacizumab-based combination with fractioned cisplatin and daily oral etoposide. We designed a phase II trial to evaluate in advanced NSCLC patients the antitumor activity and the safety of this novel regimen. In particular, 45 patients (36 males and 9 females), with a mean age of 54 years, an ECOG ≤2, stage III B/IV and NSCLC (28 adenocarcinomas, 11 squamous-cell carcinomas, 2 large-cell carcin…
Progression of coronary artery calcification and cardiac events in patients with chronic renal disease not receiving dialysis
2011
We tested for the presence of coronary calcifications in patients with chronic renal disease not on dialysis and studied its progression in 181 consecutive non-dialyzed patients who were followed for a median of 745 days. Coronary calcifications (calcium score) were tallied in Agatston units by computed tomography, and the patients were stratified into two groups by their baseline calcium score (100 U or less and over 100 U). Survival was measured by baseline calcium score and its progression. Cardiac death and myocardial infarction occurred in 29 patients and were significantly more frequent in those patients with calcium scores over 100 U (hazard ratio of 4.11). With a calcium score of 10…
STUDIO MULTICENTRICO IN NETWORK DI CENTRI UNIVERSITARI ITALIANI SULLA PREVALENZA DELL’INFEZIONE TUBERCOLARE LATENTE (ITBL) IN STUDENTI DI AREA SANITA…
2021
Introduzione. La tubercolosi (TB) rappresenta ancora oggi un problema di salute pubblica a livello globale. Sebbene l’incidenza mostri ampie differenze geografiche, la TB rappresenta una delle più importanti cause di morte e quella principale da singolo agente infettivo (3). Si stima che un terzo della popolazione mondiale risulti infettata in forma latente da ceppi di Mycobacterium tuberculosis. L’infezione tubercolare latente (ITBL) e la TB costituiscono ancora oggi, un rischio professionale per gli operatori sanitari e soggetti a questi equiparati, quali studenti che svolgono attività formativa professionalizzante in ambito assistenziale. La maggior parte dei casi di malattia attiva di o…
Linee Guida della Società Italiana di Medicina del Lavoro: “Ruolo del medico del lavoro nella gestione e prevenzione della tubercolosi in ambito occu…
2021
Linee Guida della Società Italiana di Medicina del Lavoro sul ruolo del professionista Medico del lavoro nella gestione e prevenzione della tubercolosi nei vari ambiti lavorativi