Protective, antioxidant and antiproliferative activity of grapefruit integropectin on sh-sy5y cells
Tested in vitro on SH-SY5Y neuroblastoma cells, grapefruit IntegroPectin is a powerful protective, antioxidant and antiproliferative agent. The strong antioxidant properties of this new citrus pectin, and its ability to preserve mitochondrial membrane potential and morphology, severely impaired in neurodegenerative disorders, make it an attractive therapeutic and preventive agent for the treatment of oxidative stress-associated brain disorders. Similarly, the ability of this pectic polymer rich in RG-I regions, as well as in naringin, linalool, linalool oxide and limonene adsorbed at the outer surface, to inhibit cell proliferation or even kill, at high doses, neoplastic cells may have open…
Green and Direct Synthesis of Benzaldehyde and Benzyl Benzoate in One Pot
High yields of valued benzaldehyde and benzyl benzoate are obtained in one pot starting from benzyl alcohol using oxygen as only oxidant under mild conditions (2 bar O2, 100 °C) along with an ultralow amount (0.02 mol %) of Au nanoparticles heterogenized over a spherical ORMOSIL mesoporous support. The process is remarkably selective and the catalyst is stable.
Design and performance of the prototype Schwarzschild-Couder telescope camera
Journal of astronomical telescopes, instruments, and systems 8(01), 014007-1 (2022). doi:10.1117/1.JATIS.8.1.014007
INFERENCE BASED ON RESAMPLING TECHNIQUES FOR NEURAL NETWORKS IN REGRESSION MODELS
Let {Yt}, t=1,..., T be a time series generated according to the model: Yt=f(Xt)+et t=1, ..., T where f is a non linear continuous function, Xt = (X1t, X2t, ...,Xdt) is a vector of d non stochastic explanatory variables defined on a compact X belonging Rd , and {et} are zero mean random variables with constant variance. The function f in the previous model can be approximated with a feed-forward neural networks. Many authors (Hornik et al., 1989 inter alia) showed that, under general regularity conditions, a sufficiently complex single hidden layer feedforward network can approximate any member of a class of function to any degree of accuracy. Of course to consider them a statistical techni…
Neuroprotective, antioxidant and antiproliferative activity of grapefruit IntegroPectin on SH-SY5Y cells
AbstractTested in vitro on SH-SY5Y neuroblastoma cells, grapefruit IntegroPectin is a powerful neuroprotective, antioxidant and antiproliferative agent. The strong antioxidant properties of grapefruit IntegroPectin, and its ability to preserve mitochondrial membrane potential and morphology, severely impaired in neurodegenerative disorders, make this new biopolymer highly soluble in water an attractive therapeutic agent for oxidative stress-associated brain disorders. Similarly, the ability of this new citrus pectin rich in naringin, linalool, linalool oxide and limonene adsorbed at the outer surface to inhibit cell proliferation or even kill, at high doses, neoplastic cells, coupled to its…