Extracellular release of HSP60 from tumor cells occurs via various secretory pathways

Oxidative stress apoptosis in carcinogenesis: molecular players and interactions.

Heat Shock Proteins exosomal localization and levels in non-tumoral and tumoral thyroid tissues

Exosomes (EXs) secreted from cells to the extracellular environment play an important role in intercellular communication in normality and pathology. In particular, EXs contribute to cancer progression through the modulation of tumor microenvironment. Heat Shock Proteins (Hsps) are implicated in the development of carcinogenic process because they interact with many metabolic and biomolecular mechanisms of cancer cells [1]. Different studies shown that they can be released by tumors cells and that the mechanism of release is mediated by EXs pathway. In this study we performed an immunomorphological and biomolecular analysis to investigate Hsp27, Hsp60, Hsp70, Hsp90 levels expression profile…

EXTRACELLULAR RELEASE OF HSP60 FROM TUMOR CELLS

Exosomal Hsp60 in human colon cancer

Cigarette smoke affects heat-shock proteins in human lung fibroblasts: a proteomic study and identification of three expressed HSP10 variants differentially affected by stressor.

Effect of a pathogenic stressor on human HSP10.

Effect of a pathogenetic stressor on human Hsp10.

CIGARETTE SMOKE EXPOSURE DOWNREGULATES TWO ISOELECTRIC VARIANTS OF HUMAN Hsp10 IN LUNG EPITHELIAL CELLS AND FIBROBLASTS: A PROTEOMIC STUDY.

Hsp60/procaspase 3 complex formation in human cells: impact on apoptosis and carcinogenesis.