0000000000247129

AUTHOR

David J. Anschel

showing 2 related works from this author

Subthreshold low frequency repetitive transcranial magnetic stimulation selectively decreases facilitation in the motor cortex

2002

Objective: To investigate the modulatory effect of a subthreshold low frequency repetitive transcranial magnetic stimulation (rTMS) train on motor cortex excitability. Methods: The study consisted of two separate experiments. Subjects received a 10 min long subthreshold 1Hz rTMS train. In the first experiment, (single pulse paradigm), cortical excitability was assessed by measuring the amplitude of motor evoked potentials (MEPs) before and after the rTMS train. In the second experiment, a paired pulse paradigm was employed. Results: Corticospinal excitability, as measured by the MEP amplitude, was reduced by the rTMS train (experiment 1), with a significant effect lasting for about 10 min a…

AdultMaleRepetitive transcranial magnetic stimulationmedicine.medical_treatmentHuman motor cortexElectromyographyElectromagnetic FieldsPhysiology (medical)medicineHumansModulationmedicine.diagnostic_testElectromyographyPulse (signal processing)Subthreshold conductionmusculoskeletal neural and ocular physiologyMotor CortexMotor controlCortical excitabilityMiddle AgedEvoked Potentials MotorSensory SystemsIntra-cortical circuitsTranscranial magnetic stimulationElectrophysiologymedicine.anatomical_structurenervous systemNeurologyFacilitationFemaleNeurology (clinical)Nerve NetPsychologyNeuroscienceMotor cortexClinical Neurophysiology
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Intracranial measurement of current densities induced by transcranial magnetic stimulation in the human brain

2003

Transcranial magnetic stimulation (TMS) is a non-invasive technique that uses the principle of electromagnetic induction to generate currents in the brain via pulsed magnetic fields. The magnitude of such induced currents is unknown. In this study we measured the TMS induced current densities in a patient with implanted depth electrodes for epilepsy monitoring. A maximum current density of 12 microA/cm2 was recorded at a depth of 1 cm from scalp surface with the optimum stimulation orientation used in the experiment and an intensity of 7% of the maximal stimulator output. During TMS we recorded relative current variations under different stimulating coil orientations and at different points…

Electromagnetic fieldAdultMaterials sciencemedicine.medical_treatmentModels NeurologicalNuclear magnetic resonanceElectromagnetic FieldsEpilepsy Complex PartialmedicineHumansGeneral NeuroscienceSkullBrainTranscranial Magnetic StimulationElectric StimulationIntensity (physics)Magnetic fieldElectromagnetic inductionElectrodes ImplantedTranscranial magnetic stimulationElectromagnetic coiltranscranial magnetic stimulatione depth electrodes epilepsyBrain InjuriesFemaleCurrent (fluid)ArtifactsCurrent densityNeuroscience
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