0000000000247130

AUTHOR

Roland Sparing

showing 2 related works from this author

Subthreshold low frequency repetitive transcranial magnetic stimulation selectively decreases facilitation in the motor cortex

2002

Objective: To investigate the modulatory effect of a subthreshold low frequency repetitive transcranial magnetic stimulation (rTMS) train on motor cortex excitability. Methods: The study consisted of two separate experiments. Subjects received a 10 min long subthreshold 1Hz rTMS train. In the first experiment, (single pulse paradigm), cortical excitability was assessed by measuring the amplitude of motor evoked potentials (MEPs) before and after the rTMS train. In the second experiment, a paired pulse paradigm was employed. Results: Corticospinal excitability, as measured by the MEP amplitude, was reduced by the rTMS train (experiment 1), with a significant effect lasting for about 10 min a…

AdultMaleRepetitive transcranial magnetic stimulationmedicine.medical_treatmentHuman motor cortexElectromyographyElectromagnetic FieldsPhysiology (medical)medicineHumansModulationmedicine.diagnostic_testElectromyographyPulse (signal processing)Subthreshold conductionmusculoskeletal neural and ocular physiologyMotor CortexMotor controlCortical excitabilityMiddle AgedEvoked Potentials MotorSensory SystemsIntra-cortical circuitsTranscranial magnetic stimulationElectrophysiologymedicine.anatomical_structurenervous systemNeurologyFacilitationFemaleNeurology (clinical)Nerve NetPsychologyNeuroscienceMotor cortexClinical Neurophysiology
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Segregation of areas related to visual working memory in the prefrontal cortex revealed by rTMS.

2002

The functional organization of working memory (WM) in the human prefrontal cortex remains unclear. Storage and processing functions might be segregated in ventral and dorsal areas of the prefrontal cortex, respectively. If so, storage functions might be spared, irrespective of informational domain, following damage or dysfunction in dorsolateral areas. Alternatively, WM and prefrontal function in general might be segregated according to informational domains (e.g. spatial versus object-based information). In the present study we used repetitive transcranial magnetic stimulation (rTMS) to directly test these competing hypotheses. We applied rTMS to transiently and selectively disrupt the fun…

AdultMaleCognitive Neurosciencemedicine.medical_treatmentInterference theoryPosterior parietal cortexPrefrontal Cortexbehavioral disciplines and activitiesCellular and Molecular NeuroscienceElectromagnetic FieldsmedicineReaction TimeHumansPrefrontal cortexVision OcularSelf-reference effectWorking memoryMagnetic Resonance ImagingDorsolateral prefrontal cortexTranscranial magnetic stimulationmedicine.anatomical_structureMemory Short-TermVisual PerceptionPsychologyConsumer neurosciencetranscranial magnetic stimulation prefrontal cortexNeuroscienceCerebral cortex (New York, N.Y. : 1991)
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