0000000000248933

AUTHOR

Alexander Biedermann

showing 3 related works from this author

Functional Evaluation of Emphysema Using Diffusion-Weighted 3Helium-Magnetic Resonance Imaging, High-Resolution Computed Tomography, and Lung Functio…

2004

Purpose: To assess the emphysematous enlargement of distal air-spaces and concomitant large and small airway disease using diffusion-weighted 3 Helium-magnetic resonance imaging (MRI), high-resolution computed tomography (HRCT), and lung function tests (LFT). Methods: Seven patients were examined after single lung transplantation (LTx) and 1 before double LTx for various forms of emphysema. Five patients after double LTx served as controls. Patients were assessed by 3 Helium-MRI (apparent diffusion coefficient [ADC]), HRCT (mean lung density [MLD], emphysema index [El]), and LFT. Results: Transplanted lungs: mean ADC = 0.17 cm 2 /s, MLD = -848 H, El = 22%. Emphysematous lungs: mean ADC = 0.…

Malemedicine.medical_specialtyHigh-resolution computed tomographyHeliumPulmonary function testingIsotopesmedicineHumansEffective diffusion coefficientRadiology Nuclear Medicine and imagingFunctional evaluationmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingGeneral MedicineMiddle Agedrespiratory systemSingle Lung TransplantationMagnetic Resonance ImagingRespiratory Function Testsrespiratory tract diseasesLung densityPulmonary EmphysemaConcomitantFemaleRadiologyTomography X-Ray ComputedbusinessNuclear medicineLung TransplantationInvestigative Radiology
researchProduct

Structural and Functional Characterization of Chronic Obstructive Lung Disease and Emphysema Using 3He- MRI: Comparison with CT and Pulmonary Functio…

2005

mor types. For these reasons, Matrigel impregnated with angiogenic hormone, basic-Fibroblast Growth Factor (bFGF), in a mouse model has been extensively used in fundamental angiogenesis research to induce endothelial cell differentiation and successfully allow the study of different phases of the angiogenesis process. The objective of this study was to evaluate the ability of functional ultrasound imaging (fUSI) to provide data allowing the quantification of the angiogenic process, using the Matrigel model.

MatrigelPathologymedicine.medical_specialtyAngiogenic ProcessAngiogenesisbusiness.industryGrowth factormedicine.medical_treatmentmedicine.diseaseEndothelial cell differentiationObstructive lung diseasePulmonary function testingUltrasound imagingmedicineRadiology Nuclear Medicine and imagingbusinessAcademic Radiology
researchProduct

Functional Analysis in Single-Lung Transplant Recipients

2004

Objective To develop and evaluate a postprocessing tool to quantify ventilated split-lung volumes on the basis of 3 He-MRI and to apply it in patients after single-lung transplantation (SLTX). High-resolution CT (HRCT) was employed as a reference modality providing split air-filled lung volumes. Lung volumes derived from pulmonary function test results served as clinical parameters and were used as the “gold standard.” Material and methods Eight patients (mean age, 54 years) with emphysema and six patients (mean age, 58 years) with idiopathic pulmonary fibrosis. All patients were evaluated following SLTX. HRCT was performed during inspiration (slice thickness, 1 mm; increment, 10 mm). For c…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyLungmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingrespiratory systemCritical Care and Intensive Care Medicinemedicine.diseaserespiratory tract diseasesPulmonary function testingTransplantationIdiopathic pulmonary fibrosismedicine.anatomical_structureHounsfield scalemedicineLung volumesRadiologyCardiology and Cardiovascular MedicinebusinessTidal volumeChest
researchProduct