0000000000249668

AUTHOR

Enrico Collantoni

0000-0002-6730-1778

showing 3 related works from this author

Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large-scale meta-analys…

2017

People with severe mental illness (SMI) – schizophrenia, bipolar disorder and major depressive disorder – appear at risk for cardiovascular disease (CVD), but a comprehensive meta-analysis is lacking. We conducted a large-scale meta-analysis assessing the prevalence and incidence of CVD; coronary heart disease; stroke, transient ischemic attack or cerebrovascular disease; congestive heart failure; peripheral vascular disease; and CVD-related death in SMI patients (N=3,211,768) versus controls (N=113,383,368) (92 studies). The pooled CVD prevalence in SMI patients (mean age 50 years) was 9.9% (95% CI: 7.4-13.3). Adjusting for a median of seven confounders, patients had significantly higher o…

medicine.medical_specialtyCardiovascular disease; bipolar disorder; cerebrovascular disease; congestive heart failure; coronary heart disease; major depression; premature mortality; schizophrenia; severe mental illness03 medical and health sciences0302 clinical medicinesevere mental illnessMedicineCardiovascular disease severe mental illness schizophrenia bipolar disorder major depression coronary heart disease cerebrovascular disease congestive heart failure premature mortalitycoronary heart diseasePsychiatrybipolar disorderFramingham Risk Scorebusiness.industryVascular diseaseIncidence (epidemiology)Hazard ratioCorrectionOdds ratiomedicine.diseaseCardiovascular disease030227 psychiatrycerebrovascular diseaseschizophreniaPsychiatry and Mental healthcongestive heart failurepremature mortalityHeart failureMajor depressive disorderPshychiatric Mental Healthbusinessmajor depressionBody mass index030217 neurology & neurosurgery
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Serotonin transporter gene polymorphism in eating disorders: Data from a new biobank and META-analysis of previous studies.

2016

Objectives Growing interest focuses on the association between 5-HTTLPR polymorphism and eating disorders (ED), but published findings have been conflicting. Methods The Italian BIO.VE.D.A. biobank provided 976 samples (735 ED patients and 241 controls) for genotyping. We conducted a literature search of studies published up to 1 April 2015, including studies reporting on 5HTTLPR genotype and allele frequencies in obesity and/or ED. We ran a meta-analysis, including data from BIO.VE.D.A. – comparing low and high-functioning genotype and allele frequencies in ED vs. controls. Results Data from 21 studies, plus BIO.VE.D.A., were extracted providing information from 3,736 patients and 2,707 co…

medicine.medical_specialtyAnorexia Nervosa5-HTTLPR; anorexia nervosa; binge eating; bulimia nervosa; Eating disorders; Biological Psychiatry; Psychiatry and Mental Health5-HTTLPR03 medical and health sciences0302 clinical medicinebinge eatingGene FrequencymedicineHumansGenetic Predisposition to DiseaseObesityPsychiatryBulimia NervosaBiological PsychiatrySerotonin transporterBiological Specimen BanksSerotonin Plasma Membrane Transport ProteinsPolymorphism GeneticbiologyBinge eatingBulimia nervosaEating disordermedicine.diseaseBiobank030227 psychiatryPsychiatry and Mental healthEating disordersMeta-analysis5-HTTLPREating disordersbiology.proteinGene polymorphismmedicine.symptomPsychology030217 neurology & neurosurgeryThe world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
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Catechol-O-Methyltransferase (COMT) Val158Met Polymorphism and Eating Disorders: Data From a New Biobank and Meta-Analysis of Previously Published St…

2017

Objectives: We investigated whether catechol-O-methyltransferase (COMT) Val158Met polymorphism is associated with eating disorders (EDs). Methods: We conducted a systematic literature search of studies published until 15 January 2017 and added data from the Italian ‘Biobanca Veneta per i Disturbi Alimentari’ biobank, performing a meta-analysis comparing COMT Val158Met genotype and allele frequencies in EDs and anorexia nervosa (AN) or bulimia nervosa (BN) patients versus controls. Results: Ten studies plus Biobanca Veneta per i Disturbi Alimentari (ED: n = 920, controls: n = 261 controls) with 3541 ED patients (AN = 2388; BN = 233) and 3684 controls were included. There were no significant …

Anorexia NervosaGenotypeVal158MetCatechol O-MethyltransferasePolymorphism Single Nucleotidecatechol-O-methyltransferase (COMT)polymorphismFeeding and Eating DisordersGene FrequencyCase-Control Studiesmental disordersJournal ArticleHumansBulimia NervosaVal158Met; anorexia nervosa; bulimia nervosa; catechol-O-methyltransferase (COMT); polymorphismBiological Specimen BanksEuropean eating disorders review : the journal of the Eating Disorders Association
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