0000000000254444
AUTHOR
Natale L
A Nutritional Approach to the Prevention of Cancer: from Assessment to Personalized Intervention
Among lifestyle factors, nutrition is one of the most important determinants of health, and represents a pivotal element of cancer risk. Nonetheless, epidemiological evidences of the relationship between several cancers and specific foods and nutrients is still inadequate, and solid conclusions are missing. Several epidemiological studies related increased consumption of high fat diet and the risk to develop different types of cancer. Indeed, caloric restriction without malnutrition is associated to cancer prevention, due to the reduction in the activity of pro-aging pathways, of inflammation in precancerous cells, and to the increase of the apoptosis of damaged cells. Food may be also the …
Lights and shadows of cardiac magnetic resonance imaging in acute myocarditis
Cardiac magnetic resonance (CMR) is considered a primary tool for the diagnosis of acute myocarditis, due to its unique potential for non-invasive identification of the various hallmarks of the inflammatory response, with relevant impact on patient management and prognosis. Nonetheless, a marked variation in sensitivity and negative predictive value has been reported in the literature, reflecting the intrinsic drawbacks of current diagnostic criteria, which are based mainly on the use of conventional CMR pulse sequences. As a consequence, a negative exam cannot reliably exclude the diagnosis, especially in patients who do not present an infarct-like onset of disease. The introduction of new…